北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
7期
10-10,11
,共2页
全频型%突发性聋%巴曲酶%甲强龙%长春西汀%疗效
全頻型%突髮性聾%巴麯酶%甲彊龍%長春西汀%療效
전빈형%돌발성롱%파곡매%갑강룡%장춘서정%료효
Full frequency type%Sudden deafness%Batroxobin%Methylprednisolone%Changchun fluoxetine%Curative effect
目的：观察用巴曲酶联合甲强龙和长春西汀治疗全频型突发性聋的临床效果。方法：将2013年3月～2014年10月我院收治的全频型突发性聋患者78例，随机分为对照组和治疗组患者各39例。对照组患者给予甲强龙、长春西汀注射液改善内耳微循环及糖皮质激素治疗；治疗组患者则在此基础上加用巴曲酶注射液。两组治疗前后均进行血浆纤维蛋白原（FIB）测定及纯音听阈检查，比较两组的治疗效果。结果：患者经治疗后听力水平有所提高，对照组的有效率71.8%，明显低于治疗组92.3%，差异有统计学意义（P<0.05）；治疗后患者FIB水平均有所降低，治疗组降低较对照组幅度更明显，差异有统计学意义（P<0.05）。结论：巴曲酶联合甲强龙和长春西汀能显著提高全频型突发性聋患者的听力水平，改善耳内血液循环，疗效满意，值得临床深入研究运用。
目的：觀察用巴麯酶聯閤甲彊龍和長春西汀治療全頻型突髮性聾的臨床效果。方法：將2013年3月～2014年10月我院收治的全頻型突髮性聾患者78例，隨機分為對照組和治療組患者各39例。對照組患者給予甲彊龍、長春西汀註射液改善內耳微循環及糖皮質激素治療；治療組患者則在此基礎上加用巴麯酶註射液。兩組治療前後均進行血漿纖維蛋白原（FIB）測定及純音聽閾檢查，比較兩組的治療效果。結果：患者經治療後聽力水平有所提高，對照組的有效率71.8%，明顯低于治療組92.3%，差異有統計學意義（P<0.05）；治療後患者FIB水平均有所降低，治療組降低較對照組幅度更明顯，差異有統計學意義（P<0.05）。結論：巴麯酶聯閤甲彊龍和長春西汀能顯著提高全頻型突髮性聾患者的聽力水平，改善耳內血液循環，療效滿意，值得臨床深入研究運用。
목적：관찰용파곡매연합갑강룡화장춘서정치료전빈형돌발성롱적림상효과。방법：장2013년3월～2014년10월아원수치적전빈형돌발성롱환자78례，수궤분위대조조화치료조환자각39례。대조조환자급여갑강룡、장춘서정주사액개선내이미순배급당피질격소치료；치료조환자칙재차기출상가용파곡매주사액。량조치료전후균진행혈장섬유단백원（FIB）측정급순음은역검사，비교량조적치료효과。결과：환자경치료후은력수평유소제고，대조조적유효솔71.8%，명현저우치료조92.3%，차이유통계학의의（P<0.05）；치료후환자FIB수평균유소강저，치료조강저교대조조폭도경명현，차이유통계학의의（P<0.05）。결론：파곡매연합갑강룡화장춘서정능현저제고전빈형돌발성롱환자적은력수평，개선이내혈액순배，료효만의，치득림상심입연구운용。
Objective:To observe the clinical effect of batroxobin combined with methylprednisolone in Changchun fluoxetine treatment of full frequency type of sudden deafness. Methods:78 patients with full frequency type of sudden deafness in 2013 March to 2014 October in our hospital of patients, randomly divided into the treatment group and the control group with 39 cases in each. Patients in control group were treated with methylprednisolone, Vinpocetine Injection improve inner ear microcirculation and glucocorticoid therapy;treatment group patients based on the use of Batroxobin Injection. The two groups before and after treatment were plasma fibrinogen (FIB) determination and pure tone audiometry, compare two groups of curative effect. Results:Patients been listening level after treatment, improve, control group the effective rate was 71.8%, significantly lower than the 92.3% in the treatment group, the difference was statistically significant(P<0.05);the level of FIB in patients with decreased after treatment, the treatment group decreased more significantly than the control group in amplitude, the difference was statistically significant (P<0.05). Conclusion:Batroxobin combined with methylprednisolone in Changchun fluoxetine can improve the patients full frequency type of sudden deafness hearing level, effect of the blood circulation, Gai Shaner satisfied, it is worth clinical further application.
