国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2015年
3期
189-191
,共3页
乙肝表面抗原%肝硬化%食管胃底静脉曲张破裂出血%child-pugh评分
乙肝錶麵抗原%肝硬化%食管胃底靜脈麯張破裂齣血%child-pugh評分
을간표면항원%간경화%식관위저정맥곡장파렬출혈%child-pugh평분
HBsAg%Liver cirrhosis%Esophageal variceal bleeding%Child-Pugh score
目的 对乙肝后肝硬化食管胃底静脉曲张破裂出血及child-pugh评分与血清HBsAg水平的相关性进行分析研究.方法 将82例乙肝后肝硬化患者,根据食管胃底静脉曲张破裂出血情况,分为44例未出血组(未发生食管胃底静脉曲张破裂出血)和38例出血组(发生食管胃底静脉曲张破裂出血).另外根据child-puge分级情况,将患者分为26例child-pugh A级组、33例child-pugh B级组及23例child-pughC级组.分别对各亚组间HBsAg水平含量差异进行对比,并对HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分的相关性进行分析.结果 出血组患者血清HBsAg水平含量明显高于未出血组(P＜0.05),而child-pugh C级组血清HBsAg水平含量最高(P＜0.05),child-pughA级组血清HBsAg水平含量最低(P＜0.05).同时血清HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分与均存在显著的直线相关性(P＜0.05).结论 肝硬化患者血清HBsAg水平与食管胃底静脉曲张破裂出血及child-pugh评分存在密切的相关性.
目的 對乙肝後肝硬化食管胃底靜脈麯張破裂齣血及child-pugh評分與血清HBsAg水平的相關性進行分析研究.方法 將82例乙肝後肝硬化患者,根據食管胃底靜脈麯張破裂齣血情況,分為44例未齣血組(未髮生食管胃底靜脈麯張破裂齣血)和38例齣血組(髮生食管胃底靜脈麯張破裂齣血).另外根據child-puge分級情況,將患者分為26例child-pugh A級組、33例child-pugh B級組及23例child-pughC級組.分彆對各亞組間HBsAg水平含量差異進行對比,併對HBsAg水平與食管胃底靜脈麯張破裂齣血及child-pugh評分的相關性進行分析.結果 齣血組患者血清HBsAg水平含量明顯高于未齣血組(P＜0.05),而child-pugh C級組血清HBsAg水平含量最高(P＜0.05),child-pughA級組血清HBsAg水平含量最低(P＜0.05).同時血清HBsAg水平與食管胃底靜脈麯張破裂齣血及child-pugh評分與均存在顯著的直線相關性(P＜0.05).結論 肝硬化患者血清HBsAg水平與食管胃底靜脈麯張破裂齣血及child-pugh評分存在密切的相關性.
목적 대을간후간경화식관위저정맥곡장파렬출혈급child-pugh평분여혈청HBsAg수평적상관성진행분석연구.방법 장82례을간후간경화환자,근거식관위저정맥곡장파렬출혈정황,분위44례미출혈조(미발생식관위저정맥곡장파렬출혈)화38례출혈조(발생식관위저정맥곡장파렬출혈).령외근거child-puge분급정황,장환자분위26례child-pugh A급조、33례child-pugh B급조급23례child-pughC급조.분별대각아조간HBsAg수평함량차이진행대비,병대HBsAg수평여식관위저정맥곡장파렬출혈급child-pugh평분적상관성진행분석.결과 출혈조환자혈청HBsAg수평함량명현고우미출혈조(P＜0.05),이child-pugh C급조혈청HBsAg수평함량최고(P＜0.05),child-pughA급조혈청HBsAg수평함량최저(P＜0.05).동시혈청HBsAg수평여식관위저정맥곡장파렬출혈급child-pugh평분여균존재현저적직선상관성(P＜0.05).결론 간경화환자혈청HBsAg수평여식관위저정맥곡장파렬출혈급child-pugh평분존재밀절적상관성.
Objective To analyze the possible correlation among serum HBsAg level,esophageal varices bleeding and child-pugh score in hepatitis B patients with liver cirrhosis.Methods Eighty-two patients with liver cirrhosis were divided into a non bleeding group (44 cases,without esophageal and gastric variceal hemorrhage) and a hemorrhage group (38 cases,with esophageal and gastric varices bleeding).According to the child-puge classification,26 cases belonged to grade A,33 cases were at grade B and 23 cases at grade C.HBsAg levels was tested and compared between different subgroups,and the correlation was analyzed among HBsAg levels,esophageal variceal bleeding,and Child-Pugh score.Results Serum level of HBsAg in bleeding group was significantly higher than those in no bleeding group (P ＜ 0.05).Serum level of HBsAg was the highest in Child-Pugh grade C (P ＜ 0.05),while the lowest in Child-Pugh grade A (P ＜0.05).At the same time,there was significant linear correlation among the serum level of HBsAg,esophageal variceal bleeding and Child-Pugh score (P ＜ 0.05).Conclusions There were close correlationsamong serum level of HB-sAg,esophageal variceal bleeding and Child-Pugh score in patients with liver cirrhosis.
