中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
19期
64-66
,共3页
静-静脉血液滤过%脑损伤%严重感染
靜-靜脈血液濾過%腦損傷%嚴重感染
정-정맥혈액려과%뇌손상%엄중감염
Continuous veno-venous hemofiltration (CVVH)%Cerebral injury%Severe infection
目的：探讨静-静脉血液滤过(CVVH)在脑损伤中合并严重感染患者中的临床应用价值。方法回顾性分析2011年4月~2014年4月期间收入我院的57例脑损伤合并严重感染的患者分别采用CVVH联合药物治疗或常规药物疗法在改善临床症状及预后的比较结果。对比两组治疗前及治疗后各临床指标(体温、平均动脉压、白细胞计数、CRP、PaO2/FiO2、并发症出现情况)、APACHEⅡ评分及28 d 死亡率。结果在年龄、性别、APACHEⅡ评分、器官衰竭数、机械通气率无明显差异情况下，应用CVVH治疗，其血清C反应蛋白(悦砸孕)、白细胞计数、体温、28 d死亡率、与不行CVVH治疗组比较有明显差异。结论CVVH改善脑损伤合并严重感染患者的临床症状，且采用无肝素抗凝并未明显增加患者的出血风险。应用CVVH能提高此类患者的抢救成功率。
目的：探討靜-靜脈血液濾過(CVVH)在腦損傷中閤併嚴重感染患者中的臨床應用價值。方法迴顧性分析2011年4月~2014年4月期間收入我院的57例腦損傷閤併嚴重感染的患者分彆採用CVVH聯閤藥物治療或常規藥物療法在改善臨床癥狀及預後的比較結果。對比兩組治療前及治療後各臨床指標(體溫、平均動脈壓、白細胞計數、CRP、PaO2/FiO2、併髮癥齣現情況)、APACHEⅡ評分及28 d 死亡率。結果在年齡、性彆、APACHEⅡ評分、器官衰竭數、機械通氣率無明顯差異情況下，應用CVVH治療，其血清C反應蛋白(悅砸孕)、白細胞計數、體溫、28 d死亡率、與不行CVVH治療組比較有明顯差異。結論CVVH改善腦損傷閤併嚴重感染患者的臨床癥狀，且採用無肝素抗凝併未明顯增加患者的齣血風險。應用CVVH能提高此類患者的搶救成功率。
목적：탐토정-정맥혈액려과(CVVH)재뇌손상중합병엄중감염환자중적림상응용개치。방법회고성분석2011년4월~2014년4월기간수입아원적57례뇌손상합병엄중감염적환자분별채용CVVH연합약물치료혹상규약물요법재개선림상증상급예후적비교결과。대비량조치료전급치료후각림상지표(체온、평균동맥압、백세포계수、CRP、PaO2/FiO2、병발증출현정황)、APACHEⅡ평분급28 d 사망솔。결과재년령、성별、APACHEⅡ평분、기관쇠갈수、궤계통기솔무명현차이정황하，응용CVVH치료，기혈청C반응단백(열잡잉)、백세포계수、체온、28 d사망솔、여불행CVVH치료조비교유명현차이。결론CVVH개선뇌손상합병엄중감염환자적림상증상，차채용무간소항응병미명현증가환자적출혈풍험。응용CVVH능제고차류환자적창구성공솔。
Objective To explore the clinical application value of continuous veno-venous hemofiltration (CVVH) in patients with cerebral injury complicated with severe infection. Methods A total of 57 patients with cerebral injury complicated with severe infection who were admitted to our hospital from April 2011 to April 2014 were retrospectively analyzed. They were given CVVH combined with medicinal treatment or pharmacological method respectively. The im-provement of clinical symptoms and prognosis were compared. Each clinical index before and after the treatment (body temperature, mean arterial pressure, white cell count, CRP, PaO2/FiO2, conditions of complications), APACHE II scores and 28-d mortality rate were compared between the two groups. Results Under the conditions that ages, gender, A-PACHEII scores, number of organ failure and the rate of mechanical ventilation were not significantly different, CVVH treatment was applied, and the serum CRP, white cell count, body temperature, and 28 d mortality were significantly different from those in the group who was not given the CVVH treatment. Conclusion CVVH improves the clinical symptoms of patients with cerebral injury complicated with severe infection, and anti-coagulation without heparin does not significantly improve patients' risk of bleeding. The application of CVVH is able to improve the successful rate of rescue for such type of patients.
