中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
14期
147-148
,共2页
中药%抗炎作用%途径%机理%综述
中藥%抗炎作用%途徑%機理%綜述
중약%항염작용%도경%궤리%종술
TCM medicine%Anti-inflammatory action%Pathway%Mechanism%Overview
临床大量实践证明:许多中药有不同的抗炎作用,可通过多种途径起到抗炎效果。本文主要综述了中药通过调节HPA 轴的作用,影响花生四烯酸的代谢,抗组胺、5-羟色胺及抑制白三烯 B4合成,免疫调节、抑制白细胞趋化、活化,氧自由基等途径发挥抗炎作用的机理,以期为未来更好开发、创新中药抗炎制剂提供有价值的参考。
臨床大量實踐證明:許多中藥有不同的抗炎作用,可通過多種途徑起到抗炎效果。本文主要綜述瞭中藥通過調節HPA 軸的作用,影響花生四烯痠的代謝,抗組胺、5-羥色胺及抑製白三烯 B4閤成,免疫調節、抑製白細胞趨化、活化,氧自由基等途徑髮揮抗炎作用的機理,以期為未來更好開髮、創新中藥抗炎製劑提供有價值的參攷。
림상대량실천증명:허다중약유불동적항염작용,가통과다충도경기도항염효과。본문주요종술료중약통과조절HPA 축적작용,영향화생사희산적대사,항조알、5-간색알급억제백삼희 B4합성,면역조절、억제백세포추화、활화,양자유기등도경발휘항염작용적궤리,이기위미래경호개발、창신중약항염제제제공유개치적삼고。
The clinical practice has proved that many TCM medicine have different anti-inflammatory effects, and TCM medicine can make the anti-inflammatory effect through many ways. The purpose of this article is to review the function of TCM through the regulation of the HPA axis, effect of arachidonic acid metabolism, anti-histamine, serotonin and inhibition of leukotriene B4 synthesis, immune regulation, and inhibition of leukocyte chemotaxis, activation, oxygen free radicals and other ways to play mechanism of anti-inflammatory effect, in order to better develop and innovate of TCM on anti-inflammatory agents.