医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
17期
5-5,6
,共2页
顾铭%林森森%孙立%袁胜涛
顧銘%林森森%孫立%袁勝濤
고명%림삼삼%손립%원성도
TGFβ抑制剂%肿瘤微环境%靶向治疗
TGFβ抑製劑%腫瘤微環境%靶嚮治療
TGFβ억제제%종류미배경%파향치료
TGF beta inhibitor%The tumor microenvironment%Targeted therapy
转化生长因子(TGF)β信号通路对肿瘤的进展起着关键作用,通过影响肿瘤微环境(TME)调控肿瘤生长转移、血管生成和免疫抑制等过程。TGFβ通路与肿瘤发展的密切联系使TGFβ成为肿瘤治疗靶点。
轉化生長因子(TGF)β信號通路對腫瘤的進展起著關鍵作用,通過影響腫瘤微環境(TME)調控腫瘤生長轉移、血管生成和免疫抑製等過程。TGFβ通路與腫瘤髮展的密切聯繫使TGFβ成為腫瘤治療靶點。
전화생장인자(TGF)β신호통로대종류적진전기착관건작용,통과영향종류미배경(TME)조공종류생장전이、혈관생성화면역억제등과정。TGFβ통로여종류발전적밀절련계사TGFβ성위종류치료파점。
Growth factor (TGF) signaling pathway plays a vital role on the progress of tumor, by influencing the tumor microenvironment (TME), regulating the tumor growth, angiogenesis, and immune suppression. TGF beta pathway closely connected with the development of tumor, the TGF beta targets for tumor therapy.