中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2015年
6期
619-622
,共4页
彭楠%傅先明%钱若兵%李顺利%亢志强%林彬%季学兵%魏祥品%牛朝诗
彭楠%傅先明%錢若兵%李順利%亢誌彊%林彬%季學兵%魏祥品%牛朝詩
팽남%부선명%전약병%리순리%항지강%림빈%계학병%위상품%우조시
脑震荡综合征%脑网络%度属性%功能磁共振
腦震盪綜閤徵%腦網絡%度屬性%功能磁共振
뇌진탕종합정%뇌망락%도속성%공능자공진
Post-concussion symptoms%Brain network%Degree%Functional MR imaging
目的 应用脑网络中的度属性探讨脑震荡综合征患者脑功能的变化. 方法 选择自2013年6月至2015年3月在安徽医科大学附属省立医院就诊的脑震荡综合征患者28例为患者组,同期招募23例年龄、性别、文化程度与患者组相匹配的正常被试为对照组.采集2组成员功能MRI(fMRI)数据,应用GRETNA中网络结构模块进行数据预处理得到脑网络矩阵,网络分析模块分析得到脑网络的度属性,再将度属性的结果行统计学比较以得到有差异的脑区. 结果 患者组成员与对照相比,左侧背外侧额上回、左侧后扣带回、左侧海马、左侧缘上回、左侧角回、右侧后扣带回、右侧缘上回、右侧楔前叶、右侧颞上回、右侧丘脑的度属性差异有统计学意义(P＜0.05).结论 脑震荡综合征患者相关脑区的度属性改变可能是脑震荡后脑功能障碍的原因之一.
目的 應用腦網絡中的度屬性探討腦震盪綜閤徵患者腦功能的變化. 方法 選擇自2013年6月至2015年3月在安徽醫科大學附屬省立醫院就診的腦震盪綜閤徵患者28例為患者組,同期招募23例年齡、性彆、文化程度與患者組相匹配的正常被試為對照組.採集2組成員功能MRI(fMRI)數據,應用GRETNA中網絡結構模塊進行數據預處理得到腦網絡矩陣,網絡分析模塊分析得到腦網絡的度屬性,再將度屬性的結果行統計學比較以得到有差異的腦區. 結果 患者組成員與對照相比,左側揹外側額上迴、左側後釦帶迴、左側海馬、左側緣上迴、左側角迴、右側後釦帶迴、右側緣上迴、右側楔前葉、右側顳上迴、右側丘腦的度屬性差異有統計學意義(P＜0.05).結論 腦震盪綜閤徵患者相關腦區的度屬性改變可能是腦震盪後腦功能障礙的原因之一.
목적 응용뇌망락중적도속성탐토뇌진탕종합정환자뇌공능적변화. 방법 선택자2013년6월지2015년3월재안휘의과대학부속성립의원취진적뇌진탕종합정환자28례위환자조,동기초모23례년령、성별、문화정도여환자조상필배적정상피시위대조조.채집2조성원공능MRI(fMRI)수거,응용GRETNA중망락결구모괴진행수거예처리득도뇌망락구진,망락분석모괴분석득도뇌망락적도속성,재장도속성적결과행통계학비교이득도유차이적뇌구. 결과 환자조성원여대조상비,좌측배외측액상회、좌측후구대회、좌측해마、좌측연상회、좌측각회、우측후구대회、우측연상회、우측설전협、우측섭상회、우측구뇌적도속성차이유통계학의의(P＜0.05).결론 뇌진탕종합정환자상관뇌구적도속성개변가능시뇌진탕후뇌공능장애적원인지일.
Objective To discuss the changes of brain functions in patients with post-concussion symptoms by evaluating degrees of brain network.Methods Twenty-eight patients with concussion for 3 months,admitted to our hospital from June 2013 to March 2015,and 23 volunteers paired in gender,age and education (healthy controls) were enrolled.The data were dealt with Network Construction,which was a part of GRETNA to obtain the Martix of brain network.Network Analysis was used to obtain degrees of brain network,and then,independent t-test was used to compare the degrees for significant brain regions.Results The degrees of brain regions with significant difference included left superior frontal gyrus,left posterior cingulate cortex,left hippocampus,left supramarginal gyrus,left angular gyrus,right posterior cingulate cortex,right supramarginal gyrus,right precuneus,right superior temporal gyrus and right thalamus as compared with those in healthy controls.Conclusions The changes of degrees in brain network may cause brain function deficits in patients with post-concussion symptoms.
