CAJ | 학술논문

目的：了解放尿速度对急性尿潴留(actue urinary retention,AUR)患者膀胱缺血再灌注损伤的影响。方法便利抽样法选择,2014年6－12月在上海市第七人民医院泌尿外科门诊就诊的突发 AUR患者90例为研究对象,按就诊先后将其分为对照组、观察组 A、观察组 B 各30例,放尿时设置3种不同的流速,并在放尿前(T1),放尿400 ml(T2)、600 ml(T3)、800 ml(T4)时和停止放尿后0．5 h(T5)五个时间点留取尿标本,测量并比较3组患者的尿检镜下均一红细胞、白细胞及上皮细胞数、心率、血压。结果除T5时间点的上皮细胞数外,观察组患者5个时间点尿标本的镜下均一红细胞、白细胞及上皮细胞数及患者的均低于对照组(均P＜0．05),差异有统计学意义；两组患者在T1及T4这2个时间点的血压及心率差异无统计学意义(均P＞0．05)。结论 AUR患者留置尿管后的首次放尿量控制在400 ml、放尿速度控制在150 ml/min为最佳,有利于减轻对患者膀胱组织细胞的损伤。
목적：료해방뇨속도대급성뇨저류(actue urinary retention,AUR)환자방광결혈재관주손상적영향。방법편리추양법선택,2014년6－12월재상해시제칠인민의원비뇨외과문진취진적돌발 AUR환자90례위연구대상,안취진선후장기분위대조조、관찰조 A、관찰조 B 각30례,방뇨시설치3충불동적류속,병재방뇨전(T1),방뇨400 ml(T2)、600 ml(T3)、800 ml(T4)시화정지방뇨후0．5 h(T5)오개시간점류취뇨표본,측량병비교3조환자적뇨검경하균일홍세포、백세포급상피세포수、심솔、혈압。결과제T5시간점적상피세포수외,관찰조환자5개시간점뇨표본적경하균일홍세포、백세포급상피세포수급환자적균저우대조조(균P＜0．05),차이유통계학의의；량조환자재T1급T4저2개시간점적혈압급심솔차이무통계학의의(균P＞0．05)。결론 AUR환자류치뇨관후적수차방뇨량공제재400 ml、방뇨속도공제재150 ml/min위최가,유리우감경대환자방광조직세포적손상。
Obj ective To observe the effect of the discharging rate on ischemia-reperfusion inj ury in bladder of patients with acute urinary retention.Methods By Convenience sampling,90 cases were randomly divided into ob-servation group A,observation group B and control group,with 30 cases in each group.Three different rates were set when discharging,and the urinary sample on before urination (T1),during urination (T2),600ml (T3),800 ml (T4)and 0.5h after urination (T5)were collected.According to the rate of discharging on acute urinary reten-tion.Clinical efficacies of 3 groups were observed,RBC、WBC in urine were observed before(T1)and after voiding (T2,T3,T4,T5).The isomorphic red blood cell,white blood cell,number of epithelial cells,heart rate and blood pressure were measured and compared among three groups of patients.Results The isomorphic red blood cell, white blood cell,number of epithelial cells at T2,T3 and T4 in observation group were less than which in control group(P<0.01).The heart rate and blood pressure in observation groups had no statistical significance(P>0.05). Conclusion It is better to keep the discharge rate at 150ml/min,and the initial urination volume of 400 ml after acute urinary retention which can reduce the damage of bladder histocyte.