CAJ | 학술논문

目的：探讨分析艾迪注射液联合替吉奥治疗晚期胃癌的临床疗效及其应用的安全性。方法：筛选2012年1月-2014年1月我院收治的晚期胃癌患者90例作为研究对象。采用随机数表法将所有患者随机分为实验组与对照组，每组患者45例，对照组患者采用替吉奥进行治疗，实验组接受艾迪注射液联合替吉奥治疗方案，持续性进行3个疗程，比较两组患者的治疗效果、免疫功能及毒副反应的发生情况。结果：实验组治疗总有效率为46.67%（21/45），对照组为44.44%（20/45），两组比较无显著差异，但实验组患者的生活质量评价明显高于对照组（P<0.05）；治疗后两组患者的免疫功能各项指标比较存在显著差异，同时实验组毒副反应发生率明显低于对照组（P<0.05）。结论：艾迪注射液联合替吉奥治疗晚期胃癌可在保证临床治疗效果的同时改善患者的生活质量，增强患者的免疫功能水平，降低了毒副反应的发生率。
목적：탐토분석애적주사액연합체길오치료만기위암적림상료효급기응용적안전성。방법：사선2012년1월-2014년1월아원수치적만기위암환자90례작위연구대상。채용수궤수표법장소유환자수궤분위실험조여대조조，매조환자45례，대조조환자채용체길오진행치료，실험조접수애적주사액연합체길오치료방안，지속성진행3개료정，비교량조환자적치료효과、면역공능급독부반응적발생정황。결과：실험조치료총유효솔위46.67%（21/45），대조조위44.44%（20/45），량조비교무현저차이，단실험조환자적생활질량평개명현고우대조조（P<0.05）；치료후량조환자적면역공능각항지표비교존재현저차이，동시실험조독부반응발생솔명현저우대조조（P<0.05）。결론：애적주사액연합체길오치료만기위암가재보증림상치료효과적동시개선환자적생활질량，증강환자적면역공능수평，강저료독부반응적발생솔。
Objective:To discuss clinical efficacy and safety of the Aidi injection plus Gio on advanced gastric cancer. Methods:90 cases of advanced gastric cancer in our hospital from January 2012 to January 2014 were randomly divided into the experimental group (45 cases) and the control group (45 cases). The control group were treated with Gio, the experimental group were treated with the Aidi injection plus Gio. The treating effects, immune function and the adverse response in two groups were compared in 3 courses. Results:The total efficiency in the experimental group was 46.67%(21/45);the total efficiency in the control group was 44.44%(20/45);there was no significant difference between two groups, but the quality of life in patients evaluated in the experimental group was significantly higher than that in the control group (P<0.05); there were significant differences in the immune function after treatment; the incidence of side effects in the experimental group was significantly lower than that in the control group (P<0.05). Conclusion:The Aidi injection plus Gio for advanced gastric cancer can be more effective and improve the quality of life in patients, enhance immune function in patients, reduce the adverse reaction.