医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2015年
17期
179-180
,共2页
醋酸钙%碳酸钙%高磷血症%高钙血症
醋痠鈣%碳痠鈣%高燐血癥%高鈣血癥
작산개%탄산개%고린혈증%고개혈증
Calcium acetate%Calcium carbonate%Hyperphosphatemia%Hypercalcemia
目的：探讨醋酸钙和碳酸钙治疗维持性血液透析患者高磷血症的临床疗效。方法：选择60例维持性血液透析合并高磷血症患者，随机分为醋酸钙组及碳酸钙组，每组30例，分别给予醋酸钙及碳酸钙治疗，比较两组患者治疗前后血钙及血磷水平变化及不良反应发生情况。结果：两组患者4周及8周后，血磷水平均较治疗前下降，醋酸钙组治疗第4周及第8周血磷水平低于碳酸钙组，两组患者治疗4周后血钙水平较治疗前无明显变化，治疗8周后血钙水平较治疗前升高，碳酸钙组血钙水平高于醋酸钙组，两组患者治疗4周及8周后血清甲状旁腺素水平无明显变化，两组间比较无显著差异。醋酸钙组高钙血症发生率为，碳酸钙组高钙血症发生率为，两组无显著差异。结论：醋酸钙治疗维持性血液透析患者高磷血症起效快，降磷效果好，对血钙水平影响小，具有较好的临床效果。
目的：探討醋痠鈣和碳痠鈣治療維持性血液透析患者高燐血癥的臨床療效。方法：選擇60例維持性血液透析閤併高燐血癥患者，隨機分為醋痠鈣組及碳痠鈣組，每組30例，分彆給予醋痠鈣及碳痠鈣治療，比較兩組患者治療前後血鈣及血燐水平變化及不良反應髮生情況。結果：兩組患者4週及8週後，血燐水平均較治療前下降，醋痠鈣組治療第4週及第8週血燐水平低于碳痠鈣組，兩組患者治療4週後血鈣水平較治療前無明顯變化，治療8週後血鈣水平較治療前升高，碳痠鈣組血鈣水平高于醋痠鈣組，兩組患者治療4週及8週後血清甲狀徬腺素水平無明顯變化，兩組間比較無顯著差異。醋痠鈣組高鈣血癥髮生率為，碳痠鈣組高鈣血癥髮生率為，兩組無顯著差異。結論：醋痠鈣治療維持性血液透析患者高燐血癥起效快，降燐效果好，對血鈣水平影響小，具有較好的臨床效果。
목적：탐토작산개화탄산개치료유지성혈액투석환자고린혈증적림상료효。방법：선택60례유지성혈액투석합병고린혈증환자，수궤분위작산개조급탄산개조，매조30례，분별급여작산개급탄산개치료，비교량조환자치료전후혈개급혈린수평변화급불량반응발생정황。결과：량조환자4주급8주후，혈린수평균교치료전하강，작산개조치료제4주급제8주혈린수평저우탄산개조，량조환자치료4주후혈개수평교치료전무명현변화，치료8주후혈개수평교치료전승고，탄산개조혈개수평고우작산개조，량조환자치료4주급8주후혈청갑상방선소수평무명현변화，량조간비교무현저차이。작산개조고개혈증발생솔위，탄산개조고개혈증발생솔위，량조무현저차이。결론：작산개치료유지성혈액투석환자고린혈증기효쾌，강린효과호，대혈개수평영향소，구유교호적림상효과。
Objective To investigate the calcium acetate and calcium carbonate treatment of maintenance hemodialysis patients clinical curative effect of hyperphosphatemia. Methods 60 cases of maintenance hemodialysis patients with hyperphosphatemia were selected, randomly divided into the group of calcium acetate and calcium carbonate group, 30 cases in each group, were treated with calcium acetate and calcium carbonate treatment, two groups were compared before and after treatment changes in serum calcium and phosphorus levels and the incidence of adverse reactions. Results The two groups of patients for 4 weeks and 8 weeks later, serum phosphorus levels were lower than that before treatment, calcium acetate group for fourth weeks and 8 weeks of blood phosphorus level is lower than the calcium carbonate group, treatment group two patients after 4 weeks of blood calcium levels before treatment had no obvious change, after 8 weeks of treatment, serum calcium levels were increased compared with before treatment, calcium carbonate group is higher than the level of calcium in calcium acetate group, treatment group two patients had no obvious change in 4 and 8 weeks after the serum parathyroid hormone levels, and there is no significant difference between the two groups. The incidence of hypercalcemia, calcium acetate group, calcium carbonate group the incidence of hypercalcemia, no significant difference between the two groups. Conclusion Calcium acetate in treating hemodialysis patients with hyperphosphatemia rapid onset, phosphorus reduction effect, little influence on serum calcium level, has good clinical effect.
