CAJ | 학술논문

目的：探究临床围术期肠内营养支持治疗方法在结直肠癌中的临床价值。方法选取2013年12月至2014年12月上海市闸北区北站医院胃肠外科收治的结直肠癌患者50例，采用随机数字表法随机分为试验组和对照组，各25例。试验组采取围术期的肠内营养支持治疗，对照组采取围术期的传统治疗，比较两组患者的临床疗效。结果试验组患者的术前准备情况较对照组好，手术前的胃肠道准备工作中，试验组出现不良反应2例，对照组出现不良反应10例；试验组排便次数为3次，对照组排便次数为5次；试验组口渴次数为2次，对照组口渴次数为5次；术后试验组第一次排气时间、第一次排便时间、住院时间均显著短于对照组[（55±10） h比（76±10） h，（3．6±1．5） d比（6．2±2．3） d，（5.2±1.2） d 比（10.6±2.8） d，P＜0.05或P＜0.01]；术后7 d试验组总蛋白（58±7） g／L、白蛋白（32±3） g／L、前白蛋白（170±15） mg／L、白细胞总数（1.36±0.23）×109／L、血红蛋白（100±17） g／L，低于对照组总蛋白（66±7） g／L、白蛋白（36±4） g／L、前白蛋白（210±16） mg／L、白细胞总数（1.76±0.36）×109／L、血红蛋白（112±17） g／L，差异均有统计学意义（P＜0.05）。结论围术期肠内营养支持治疗较传统的治疗手段疗效显著，可以有效地恢复肠道功能，提升患者的肠道的营养状况和免疫情况，值得临床进一步推广。
목적：탐구림상위술기장내영양지지치료방법재결직장암중적림상개치。방법선취2013년12월지2014년12월상해시갑북구북참의원위장외과수치적결직장암환자50례，채용수궤수자표법수궤분위시험조화대조조，각25례。시험조채취위술기적장내영양지지치료，대조조채취위술기적전통치료，비교량조환자적림상료효。결과시험조환자적술전준비정황교대조조호，수술전적위장도준비공작중，시험조출현불량반응2례，대조조출현불량반응10례；시험조배편차수위3차，대조조배편차수위5차；시험조구갈차수위2차，대조조구갈차수위5차；술후시험조제일차배기시간、제일차배편시간、주원시간균현저단우대조조[（55±10） h비（76±10） h，（3．6±1．5） d비（6．2±2．3） d，（5.2±1.2） d 비（10.6±2.8） d，P＜0.05혹P＜0.01]；술후7 d시험조총단백（58±7） g／L、백단백（32±3） g／L、전백단백（170±15） mg／L、백세포총수（1.36±0.23）×109／L、혈홍단백（100±17） g／L，저우대조조총단백（66±7） g／L、백단백（36±4） g／L、전백단백（210±16） mg／L、백세포총수（1.76±0.36）×109／L、혈홍단백（112±17） g／L，차이균유통계학의의（P＜0.05）。결론위술기장내영양지지치료교전통적치료수단료효현저，가이유효지회복장도공능，제승환자적장도적영양상황화면역정황，치득림상진일보추엄。
Objective To explore the clinical value of perioperative enteral nutrition support treatment for colorectal cancer.Methods Between Dec.2013 and Dec.2014, from Shanghai Zhabei North Station Hospital,50 patients with colorectal cancer admitted to gastrointestinal surgery were included in the study , using the random number table method, they were randomly divided into trial group and control group(n=25),the trial group was given perioperative enteral nutrition support treatment,while the control group adopted traditional perioperative treatment,and the clinical curative effect of different treatment means was compared.Results The preoperative preparation of the trial group was better than the control group:during the gastrointestinal preparation before operation,there were 2 cases of adverse reactions in the trail group, while there were 10 cases in the control group;defecate number of the trial group was 3 , of the control group was 5 time;thirst number of the trial group was 2,of the control group was 5;exhaust time,postoperative defe-cation time and hospitalization time of the trial group were significantly shorter than the control group[(55 ± 10) h vs (76 ±10) h,(3.6 ±1.5) d vs (6.2 ±2.3) d,(5.2 ±1.2) d vs (10.6 ±2.8) d,P<0.05 or P<0.01]; postoperative day 7:total protein(58 ±7) g/L,albumin(32 ±3) g/L,prealbumin(170 ±15) mg/L, total number of white blood cells (1.36 ±0.23) ×109/L, heruoglobin(100 ±17) g/L of the trial group were all lower than the control group [(66 ±7) g/L,(36 ±4) g/L,(210 ±16) mg/L,(1.76 ±0.36) × 109/L,(112 ±17) g/L],with statistically significant diffrence(P<0.05).Conclusion Perioperative en-teral nutrition support has obvious therapeutic effect than traditional treatments,which can effectively recover the intestinal function,improve the intestinal nutrition status and immune condition,thus is worth further pro-motion in the clinical practice.