临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2015年
18期
10-11
,共2页
高血压%半胱氨酸
高血壓%半胱氨痠
고혈압%반광안산
Hypertension%Cysteine
目的：探讨血清同型半胱氨酸（Hcy）水平与高血压的相关性。方法选取孟津县中医院2013年6月—2014年6月收治的高血压患者60例作为观察组，选择同期接受健康体检的健康人60例作为对照组。比较两组受检者血清 Hcy 水平以及不同高血压分级患者血清 Hcy 水平。结果观察组患者血清 Hcy 水平、高同型半胱氨酸血症发生率高于对照组，差异有统计学意义（P ﹤0.05）。3级高血压患者血清 Hcy 水平高于1级高血压，2级高血压患者高同型半胱氨酸血症发生率高于1级高血压，3级高血压高同型半胱氨酸血症发生率高于1级高血压，差异有统计学意义（P ﹤0.05）；收缩压、舒张压与血清 Hcy 水平均呈正相关（r ＝0.921、0.884，P ﹤0.05）。结论血清 Hcy 水平增高是高血压的独立危险因素，对其进行有效的干预对于控制高血压的发生，降低其发病率具有十分重要的意义。
目的：探討血清同型半胱氨痠（Hcy）水平與高血壓的相關性。方法選取孟津縣中醫院2013年6月—2014年6月收治的高血壓患者60例作為觀察組，選擇同期接受健康體檢的健康人60例作為對照組。比較兩組受檢者血清 Hcy 水平以及不同高血壓分級患者血清 Hcy 水平。結果觀察組患者血清 Hcy 水平、高同型半胱氨痠血癥髮生率高于對照組，差異有統計學意義（P ﹤0.05）。3級高血壓患者血清 Hcy 水平高于1級高血壓，2級高血壓患者高同型半胱氨痠血癥髮生率高于1級高血壓，3級高血壓高同型半胱氨痠血癥髮生率高于1級高血壓，差異有統計學意義（P ﹤0.05）；收縮壓、舒張壓與血清 Hcy 水平均呈正相關（r ＝0.921、0.884，P ﹤0.05）。結論血清 Hcy 水平增高是高血壓的獨立危險因素，對其進行有效的榦預對于控製高血壓的髮生，降低其髮病率具有十分重要的意義。
목적：탐토혈청동형반광안산（Hcy）수평여고혈압적상관성。방법선취맹진현중의원2013년6월—2014년6월수치적고혈압환자60례작위관찰조，선택동기접수건강체검적건강인60례작위대조조。비교량조수검자혈청 Hcy 수평이급불동고혈압분급환자혈청 Hcy 수평。결과관찰조환자혈청 Hcy 수평、고동형반광안산혈증발생솔고우대조조，차이유통계학의의（P ﹤0.05）。3급고혈압환자혈청 Hcy 수평고우1급고혈압，2급고혈압환자고동형반광안산혈증발생솔고우1급고혈압，3급고혈압고동형반광안산혈증발생솔고우1급고혈압，차이유통계학의의（P ﹤0.05）；수축압、서장압여혈청 Hcy 수평균정정상관（r ＝0.921、0.884，P ﹤0.05）。결론혈청 Hcy 수평증고시고혈압적독립위험인소，대기진행유효적간예대우공제고혈압적발생，강저기발병솔구유십분중요적의의。
Objective To investigate the correlation between serum homocysteine levels and hypertension. Methods In Mengjin County Hospital from June 2013 to June 2014,a total of 60 hypertensive patients were selected as the observation group,a total of 60 healthy people were selected as the control group. Serum homocysteine levels of the two groups and patients with different levels of homocysteinegrade were compared. Results Serum homocysteine levels,incidence of hyperhomocys-teinemia of observation group were higher than those of control group,the differences were statistically significant(P ﹤ 0. 05). Serum homocysteine levels of level 3 hypertension patients were higher than level 1 hypertension,incidence of hyperhomocys-teinemia of level 2 hypertension patients was higher than level 1 hypertension,the incidence of hyperhomocysteinemia of level 3 hypertension patients was higher than level 1 hypertension,the differences were statistically significant(P ﹤ 0. 05). Systolic blood pressure,diastolic blood pressure were positively correlated with serum homocysteine levels( r = 0. 921,0. 884,P ﹤0. 05). Conclusion The increased serum homocysteine level is an independent risk factor for hypertension and its effective in-tervention is of great importance for the control of high blood pressure.
