CAJ | 학술논문

目的：研究分析中医汤剂对乳腺癌化疗患者的骨髓抑制及免疫功能指标水平的影响。方法：选择96例乳腺癌化疗患者，以数字法随机分成观察组（48例）和对照组（48例）。对照组采用单纯化疗，观察组则在化疗期间加用中医汤剂治疗。观察并对比两组化疗前后血小板、血红蛋白和白细胞变化情况，分析对患者骨髓抑制及免疫功能水平的影响。结果：观察组血小板、血红蛋白和白细胞降低程度均显著低于对照组；观察组患者治疗后CD3、CD4、CD8、CD4/CD8和NK细胞活性指标均显著高于治疗前及治疗后的对照组，差异均有统计学意义（均P＜0.05）。结论：中医汤剂配合化疗对乳腺癌患者治疗具有较好效果，对患者骨髓抑制有较大的减轻改善作用，且对患者免疫功能各项指标水平具有增强的效果。
목적：연구분석중의탕제대유선암화료환자적골수억제급면역공능지표수평적영향。방법：선택96례유선암화료환자，이수자법수궤분성관찰조（48례）화대조조（48례）。대조조채용단순화료，관찰조칙재화료기간가용중의탕제치료。관찰병대비량조화료전후혈소판、혈홍단백화백세포변화정황，분석대환자골수억제급면역공능수평적영향。결과：관찰조혈소판、혈홍단백화백세포강저정도균현저저우대조조；관찰조환자치료후CD3、CD4、CD8、CD4/CD8화NK세포활성지표균현저고우치료전급치료후적대조조，차이균유통계학의의（균P＜0.05）。결론：중의탕제배합화료대유선암환자치료구유교호효과，대환자골수억제유교대적감경개선작용，차대환자면역공능각항지표수평구유증강적효과。
Objective: To study the effect of TCM Decoction on bone marrow suppression and immune function indexes of breast cancer patients with chemotherapy. Methods: 96 cases of breast cancer patients with chemotherapy were randomly divided into observation group (48 cases) and control group (48 cases). The control group was treated by chemotherapy; the observation group was added with TCM Decoction treatment during chemotherapy. Blood platelet, hemoglobin and white blood cell changes of the two groups before and after treatment were observed and the effect on bone marrow suppression and immune function level were analyzed. Results: In the observation group, the decreasing degree of platelet, hemoglobin and white blood cells was significantly lower than that of the control group; the observation group, the CD3, CD4, CD8, CD4/CD8 and NK cell activity index after treatment were higher than that before and after treatment of the control group, the differences were statistically significant (allP<0.05). Conclusion: The traditional Chinese medicine decoction combined with chemotherapy has a good effect on the treatment of patients with breast cancer; it had a greater reduction effect on bone marrow inhibition and enhancement effect on various indicators of immune function.