医学综述
醫學綜述
의학종술
MEDICAL RECAPITULATE
2015年
12期
2223-2225,2228
,共4页
刘彬%孙红霞%王燕(综述)%韩荣(审校)
劉彬%孫紅霞%王燕(綜述)%韓榮(審校)
류빈%손홍하%왕연(종술)%한영(심교)
代谢综合征%Th17细胞%调节性T细胞%免疫炎症反应
代謝綜閤徵%Th17細胞%調節性T細胞%免疫炎癥反應
대사종합정%Th17세포%조절성T세포%면역염증반응
Metabolic syndrome%Th17 cells%Regulatory T cells%Immune and inflammatory
代谢综合征的发生是复杂的遗传与环境因素相互作用的结果。其发病机制尚未完全明确,近年研究发现适应性免疫及固有性免疫介导的炎症反应机制在代谢综合征的发生、发展中起一定的作用,不同亚群的淋巴细胞及其细胞因子参与代谢综合征组分的发生与发展,其中 Th17细胞及调节性T细胞与代谢综合征的关系已受到关注,并取得了一定的研究成果,开辟了代谢综合征的免疫治疗这个全新的领域。
代謝綜閤徵的髮生是複雜的遺傳與環境因素相互作用的結果。其髮病機製尚未完全明確,近年研究髮現適應性免疫及固有性免疫介導的炎癥反應機製在代謝綜閤徵的髮生、髮展中起一定的作用,不同亞群的淋巴細胞及其細胞因子參與代謝綜閤徵組分的髮生與髮展,其中 Th17細胞及調節性T細胞與代謝綜閤徵的關繫已受到關註,併取得瞭一定的研究成果,開闢瞭代謝綜閤徵的免疫治療這箇全新的領域。
대사종합정적발생시복잡적유전여배경인소상호작용적결과。기발병궤제상미완전명학,근년연구발현괄응성면역급고유성면역개도적염증반응궤제재대사종합정적발생、발전중기일정적작용,불동아군적림파세포급기세포인자삼여대사종합정조분적발생여발전,기중 Th17세포급조절성T세포여대사종합정적관계이수도관주,병취득료일정적연구성과,개벽료대사종합정적면역치료저개전신적영역。
The metabolic syndrome is the result of a complex interaction of genetic and environmental factors.Its pathogenesis remains poorly understood , recent studies have found that adaptive immunity and innate immune-mediated inflammatory mechanisms played a certain role in the development of the metabolic syndrome.Different subsets of lymphocytes and cytokines, different subsets of lymphocytes and cytokines especially Th17 cells and regulatory T cells,are involved in the origin and development of the components of the metabolic syndrome,which opened up a new field of immune treatment of metabolic syndrome.