CAJ | 학술논문

目的：对尼莫地平用于高血压脑出血治疗的临床效果进行探讨分析。方法选取2012年8月-2014年8月于该院进行救治的498例高血压脑出血患者，将其随机分为观察组250例与对照组248例，其中对照组采用常规治疗，观察组在对照组的基础上，加用尼莫地平治疗。并且对治疗效果进行观察记录。结果观察组总有效率为92.4%，对照组总有效率为82.6%，明显低于观察组(χ2=8.4471,P<0.05)；治疗后，观察组三项指标院血肿体积、水肿面积、神经功能评分均比对照组改善明显，各指标内相比差异有统计学意义(P<0.05)；两组患者不良反应率差异无统计学意义(χ2=4.9381,P>0.05)。结论尼莫地平治疗高血压脑出血具有疗效好，不良反应低等优点。
목적：대니막지평용우고혈압뇌출혈치료적림상효과진행탐토분석。방법선취2012년8월-2014년8월우해원진행구치적498례고혈압뇌출혈환자，장기수궤분위관찰조250례여대조조248례，기중대조조채용상규치료，관찰조재대조조적기출상，가용니막지평치료。병차대치료효과진행관찰기록。결과관찰조총유효솔위92.4%，대조조총유효솔위82.6%，명현저우관찰조(χ2=8.4471,P<0.05)；치료후，관찰조삼항지표원혈종체적、수종면적、신경공능평분균비대조조개선명현，각지표내상비차이유통계학의의(P<0.05)；량조환자불량반응솔차이무통계학의의(χ2=4.9381,P>0.05)。결론니막지평치료고혈압뇌출혈구유료효호，불량반응저등우점。
Objective To investigate the application of nimodipine in treating Hypertensive Cerebral Hemorrhage. Methods 498 in-patients with hypertensive cerebral hemorrhage treated in our hospital from August 2012 to August 2014 were selected and randomly divided into observation group and control group. 248 patients in the control received routine treatment, while 250 pa-tients in the observation group was given nimodipine injection based on routine treatment. The therapeutic effectiveness of the two groups was compared. Results The total efficiency of the observation group was 92.4%, which was higher than 82.6% of the con-trol group(P<0.05); The absorption of hemorrhage, edema and ESS were better in the observation group(P<0.05); no obvious dif-ferences of adverse reaction were observed between the two groups (P>0.05). Conclusion Nimodipine injection in the treatment of patients with HCT has the advantages of remarkable effect and low incidence of adverse reaction. benefit for the absorption of hemorrhage and edema and the improvement of neurological function of patient, which should be widely applied in clinic.