CAJ | 학술논문

骨质疏松的发生、发展与成骨细胞增殖、分化、凋亡和自噬等功能密切相关。活性氧（ ROS）所致的氧化应激影响成骨细胞功能。本文对氧化应激影响成骨细胞功能的分子机制及与自噬与凋亡、增殖、分化间的相互联系作一综述。
골질소송적발생、발전여성골세포증식、분화、조망화자서등공능밀절상관。활성양（ ROS）소치적양화응격영향성골세포공능。본문대양화응격영향성골세포공능적분자궤제급여자서여조망、증식、분화간적상호련계작일종술。
Osteoporosis (OP) is an metabolic bone disease that affects human health, and its initiation and progress are closely related with the osteoblast function, such as proliferation, differentiation, apoptosis, and autophagy.ROS, the main source of oxidation stress, affects osteoblast function.To date, the research in mecha-nisms of oxidation stress on osteoblast function and relationship between autophagy and apoptosis, proliferation and differentiation have made great progress, and this paper makes a review about research of oxidation stress in regula-tion of osteoblast function.