CAJ | 학술논문

目的：探讨吉莱骨粉（ GeneX）可吸收骨水泥用于强化聚甲基丙烯酸甲酯骨水泥（ polymethyl－methacrylate， PMMA）成形椎体的邻近椎体，预防邻近椎体再骨折的临床效果。方法收集2010年11月至2011年11月在北京友谊医院骨科行多发椎体压缩骨折椎体成形术治疗的患者15例，使用GeneX对与填充PMMA椎体的相邻节段进行强化，观察术后强化椎体的高度变化及再骨折发生率。结果术后6个月、1年随访结果显示，强化椎体前、中、后部高度及Cobbs’角较术后即刻影像均未见明显差异， GeneX骨水泥吸收良好。再发椎体骨折1例，为非强化椎体。结论应用GeneX骨水泥对多发椎体压缩骨折手术椎体邻近椎体进行强化，术后高度保持良好，对椎体成形术后邻近椎体再骨折的预防具有一定临床意义。
목적：탐토길래골분（ GeneX）가흡수골수니용우강화취갑기병희산갑지골수니（ polymethyl－methacrylate， PMMA）성형추체적린근추체，예방린근추체재골절적림상효과。방법수집2010년11월지2011년11월재북경우의의원골과행다발추체압축골절추체성형술치료적환자15례，사용GeneX대여전충PMMA추체적상린절단진행강화，관찰술후강화추체적고도변화급재골절발생솔。결과술후6개월、1년수방결과현시，강화추체전、중、후부고도급Cobbs’각교술후즉각영상균미견명현차이， GeneX골수니흡수량호。재발추체골절1례，위비강화추체。결론응용GeneX골수니대다발추체압축골절수술추체린근추체진행강화，술후고도보지량호，대추체성형술후린근추체재골절적예방구유일정림상의의。
Objective Exploring the clinical result of GeneXresorbable bone cement to reinforce the vertebra adjacent to the PMMA filled vertebral bodies and the function for preventing the refractures after vertebroplasty.Methods Collecting 15 patients with multiple OVCF cured by vertebroplasty from Nov 2010 to Nov 2011, using GeneX for the aug-mentation of stable vertebrae adjacent to the PMMA filled vertebral bodies.Maintenance of augmented vertebral height and alignment of the stable vertebra at 6 months and 1 year compared to baseline using diagnostric radiography.Results Ac-cording to the X-Ray at 6 months and 1 year after the augmentation compared with immediate postoperative images, there is no significant difference on the height and Cobbs’angle of augmented vertebra.Conclusion The augmentation of sta-ble vertebrae adjacent to the PMMA filled vertebral bodies using GeneX has some preventive effects on the refractures after vertebroplasty.