CAJ | 학술논문

目的：探讨甲状腺近全切除术治疗弥漫性结节性甲状腺肿的可行性，为临床上疾病的治疗提供科学依据。方法以100例弥漫性结节性甲状腺肿患者作为研究对象，随机均分为实验组和对照组（n=50）。对照组患者接受甲状腺肿全切术进行治疗，实验组患者则接受甲状腺近全切术进行，进行半年随访后，对比观察2组患者的临床治疗效果。结果实验组患者手术时间为(96.14±2.34)min，对照组患者手术时间为(128.36±2.56)min，实验组患者住院时间为(7.34±2.67)d，而对照组患者住院时间为(11.56±2.36)d，实验组患者治疗后疾病复发人数为9例，复发率为18%，对照组患者疾病复发人数为15例，复发率为30%；实验组患者发生不良反应人数为4例(8%)，对照组发生不良反应人数为14例(28%)，实验组在手术时间、住院时间、疾病复发以及并发症发生方面均明显低于对照组，差异具有统计学意义(P<0.05)。结论使用甲状腺近全切术进行弥漫性结节性甲状腺肿的治疗，具有较好的治疗效果，降低了术后疾病分复发率以及并发症的发生，值得在临床上推广和使用。
목적：탐토갑상선근전절제술치료미만성결절성갑상선종적가행성，위림상상질병적치료제공과학의거。방법이100례미만성결절성갑상선종환자작위연구대상，수궤균분위실험조화대조조（n=50）。대조조환자접수갑상선종전절술진행치료，실험조환자칙접수갑상선근전절술진행，진행반년수방후，대비관찰2조환자적림상치료효과。결과실험조환자수술시간위(96.14±2.34)min，대조조환자수술시간위(128.36±2.56)min，실험조환자주원시간위(7.34±2.67)d，이대조조환자주원시간위(11.56±2.36)d，실험조환자치료후질병복발인수위9례，복발솔위18%，대조조환자질병복발인수위15례，복발솔위30%；실험조환자발생불량반응인수위4례(8%)，대조조발생불량반응인수위14례(28%)，실험조재수술시간、주원시간、질병복발이급병발증발생방면균명현저우대조조，차이구유통계학의의(P<0.05)。결론사용갑상선근전절술진행미만성결절성갑상선종적치료，구유교호적치료효과，강저료술후질병분복발솔이급병발증적발생，치득재림상상추엄화사용。
Objective To observe the feasibility of near-total throidectomy treating diffuse and nodular goiter, for providing scientiifc theoretical basis for treating clinical disease. Methods 100 cases with diffuse and nodular goiter were selected as research objects and divided into two groups randomly, the experiment group and the control group(n=50). The control group was treated with total thyroidectomy, and the experiment group was treated with near-total thyroidectomy. After following up for half a year, the clinical treatment effect of two groups was compared. Results Experimental operation time patients was (96.14±2.34) min, control group patients with surgical time is (128.36±2.56) min, the experimental group patients hospitalized for d (7.34±2.67), while the control group patients hospitalized for d (11.56±2.36), the experimental group number for 9 cases of patients relapse after treatment, the recurrence rate was 18%, control group patients relapse number for 15 patients, the recurrence rate was 30%;Number of adverse reactions for 4 cases of experimental group (8%), control the number of adverse reactions in 14 cases (28%). The operation time, length of stay, disease recurrence and complications of the experiment group was evidently lower than that of the control group, which had statistical signiifcance (P<0.05). Conclusion Near-total throidectomy treating diffuse and nodular goiter not only has good treatment effect, but also can reduce the recurrence rate of disease after operation and complications, which is worthy of clinical promotion and application.