中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
15期
61-63
,共3页
中药配方颗粒和肝化纤方%肝纤维化%肝功能
中藥配方顆粒和肝化纖方%肝纖維化%肝功能
중약배방과립화간화섬방%간섬유화%간공능
TCM formula granule and decoction for liver fibrosis%Liver fibrosis%Liver function
目的：观察分析中药配方颗粒和肝化纤方治疗肝纤维化的临床疗效。方法：回顾性分析我院2012年7月—2013年7月期间收治的60例乙肝肝纤维化患者的临床资料，将其平均分成对照组和观察组，给予对照组采用益肝康胶囊（院内制剂）治疗，观察组用中药配方颗粒和肝化纤方治疗，3次/d，3个月为1个疗程，比较分析两组治疗效果。结果：与对照组相比，观察组采用中药配方颗粒和肝化纤方治疗以后，临床各项症状显著改善，两组比较差异显著，具有统计学意义（P＞0.05）。治疗后两组肝纤维化的四项指标均有所改善，但观察组各项值下降幅度更为明显（P＜0.05）。两组治疗前、后相比，患者的ALT、AST以及TBIL都出现了明显的下降，但是观察组下降幅度更大，两组相比，差异明显（P＜0.05）；同时两组的ALB、A/G都明显上升，且观察组上升幅度更大（P＜0.05）。在治疗后两组患者的门脉内径、脾厚度以及 A/P，和治疗前相比都有明显缩小或者下降，但观察组下降更明显（P＜0.05）；在治疗后观察组患者的门静脉内径、A/P明显变小（P＜0.05），但是对照组却无明显变化。结论：中药配方颗粒和肝化纤方治疗乙肝肝纤维化，疗效显著，值得临床推广运用。
目的：觀察分析中藥配方顆粒和肝化纖方治療肝纖維化的臨床療效。方法：迴顧性分析我院2012年7月—2013年7月期間收治的60例乙肝肝纖維化患者的臨床資料，將其平均分成對照組和觀察組，給予對照組採用益肝康膠囊（院內製劑）治療，觀察組用中藥配方顆粒和肝化纖方治療，3次/d，3箇月為1箇療程，比較分析兩組治療效果。結果：與對照組相比，觀察組採用中藥配方顆粒和肝化纖方治療以後，臨床各項癥狀顯著改善，兩組比較差異顯著，具有統計學意義（P＞0.05）。治療後兩組肝纖維化的四項指標均有所改善，但觀察組各項值下降幅度更為明顯（P＜0.05）。兩組治療前、後相比，患者的ALT、AST以及TBIL都齣現瞭明顯的下降，但是觀察組下降幅度更大，兩組相比，差異明顯（P＜0.05）；同時兩組的ALB、A/G都明顯上升，且觀察組上升幅度更大（P＜0.05）。在治療後兩組患者的門脈內徑、脾厚度以及 A/P，和治療前相比都有明顯縮小或者下降，但觀察組下降更明顯（P＜0.05）；在治療後觀察組患者的門靜脈內徑、A/P明顯變小（P＜0.05），但是對照組卻無明顯變化。結論：中藥配方顆粒和肝化纖方治療乙肝肝纖維化，療效顯著，值得臨床推廣運用。
목적：관찰분석중약배방과립화간화섬방치료간섬유화적림상료효。방법：회고성분석아원2012년7월—2013년7월기간수치적60례을간간섬유화환자적림상자료，장기평균분성대조조화관찰조，급여대조조채용익간강효낭（원내제제）치료，관찰조용중약배방과립화간화섬방치료，3차/d，3개월위1개료정，비교분석량조치료효과。결과：여대조조상비，관찰조채용중약배방과립화간화섬방치료이후，림상각항증상현저개선，량조비교차이현저，구유통계학의의（P＞0.05）。치료후량조간섬유화적사항지표균유소개선，단관찰조각항치하강폭도경위명현（P＜0.05）。량조치료전、후상비，환자적ALT、AST이급TBIL도출현료명현적하강，단시관찰조하강폭도경대，량조상비，차이명현（P＜0.05）；동시량조적ALB、A/G도명현상승，차관찰조상승폭도경대（P＜0.05）。재치료후량조환자적문맥내경、비후도이급 A/P，화치료전상비도유명현축소혹자하강，단관찰조하강경명현（P＜0.05）；재치료후관찰조환자적문정맥내경、A/P명현변소（P＜0.05），단시대조조각무명현변화。결론：중약배방과립화간화섬방치료을간간섬유화，료효현저，치득림상추엄운용。
Objective: To observe the clinical curative effect of TCM formula granule and decoction for liver fibrosis of liver fiber. Methods:Retrospectively analyzed the clinical data of 60 patients admitted to our hospital from July 2012 to July 2013 with hepatic fibrosis of hepatitis B patients, They were divided into the observation group and the control group.The control group was given Yigankang capsule (hospital preparations) treatment and the observation group was given formula of traditional Chinese Medicine and liver fibrosis.Both groups took medicine 3 times a day,3 month as a treatment course. The therapeutic effect of the two groups was compared and analyzed. Results: Compared with the control group,the clinical symptoms of the observation group improved significantly, the difference between the two groups was significant(P>0.05).After treatment,the four indexes of hepatic fibrosis of the two groups were improved, but the observation group decreased more significant (P<0.05).Compared with before treatment,the AST,ALT and TBIL of the two groups after treatment were significantly decreased, but the observation group decreased more, and there was significant difference (P<0.05);ALB,A and G of the two groups increased significantly,and the observation group rose more steeply (P<0.05).Compared with before treatment, the diameter of the portal vein,thickness of spleen and A/P of two groups after the treatment, significantly decreased,but the observation group decreased more significantly (P<0.05);the diameter of portal vein and A/P of the observation group were significantly decreased after treatment (P< 0.05),but the control group had no obvious changes.Conclusion:TCM formula granule and decoction for chronic hepatitis B with hepatic fibrosis had significant effect, so it is worthy of clinical application.
