CAJ | 학술논문

目的：评价抗菌药物专项整治前后剖宫产预防用抗菌药物的变化及效果。方法采用回顾性分析方法，随机抽取本院归档病历，依据抗菌药物临床应用指导原则，对其进行分析研究。2011年1~4月未实施抗菌药物专项活动整治前的600份病历与2012同期抽取的专项整治活动后的病例作对比，比较抗菌药物的选择、用药时机、用药疗程、联合用药情况。结果整治后，抗菌药物的选择全部为非限制级抗菌药物；联合用药率由10.00%下降到0.67%；剖宫产预防用抗菌药物给药时机为断脐后的使用率提高到92.83%；24 h的停药率由1.17%提高到39.83%。结论整治措施得力，效果显著，临床用药需进一步规范。
목적：평개항균약물전항정치전후부궁산예방용항균약물적변화급효과。방법채용회고성분석방법，수궤추취본원귀당병력，의거항균약물림상응용지도원칙，대기진행분석연구。2011년1~4월미실시항균약물전항활동정치전적600빈병력여2012동기추취적전항정치활동후적병례작대비，비교항균약물적선택、용약시궤、용약료정、연합용약정황。결과정치후，항균약물적선택전부위비한제급항균약물；연합용약솔유10.00%하강도0.67%；부궁산예방용항균약물급약시궤위단제후적사용솔제고도92.83%；24 h적정약솔유1.17%제고도39.83%。결론정치조시득력，효과현저，림상용약수진일보규범。
Objective To evaluate the change and effect of preventive antibiotics for cesarean section before and after specific rectification of antibiotics. Methods Retrospective analysis was applied.Filed medical records in our hospital were randomly selected,analyzed and studied according to the clinical application guidance principle for antibiotics.600 medical records before the specific rectification of antibiotics from January to April 2011 and medical records after the specific rectification of antibiotics in the same period in 2012 were compared.Selection of antibiotics,opportunity for drug use,course of drug and drug combination were compared. Results After the specific rectification,all selected an-tibiotics were non-restricted antibiotics;the drug combination rate reduced from 10.00% to 0.67%;use rate after break-ing the umbilical cord for administration time of preventive antibiotics for cesarean section improved to 92.83%;24-hour drug of withdrawal rate increased from 1.17% to 39.83%. Conclusion The specific rectification of antibiotics is significantly effective,and clinical drug use should be further standardized.