中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
17期
143-145
,共3页
疏肝和胃降逆汤%反流性食管炎%作用机制
疏肝和胃降逆湯%反流性食管炎%作用機製
소간화위강역탕%반류성식관염%작용궤제
Shugan Hewei Jiangni decoction%Reflux esophagitis%Functional mechanism
目的：探讨疏肝和胃降逆汤治疗反流性食管炎的效果。方法选取本院2012年1月~2014年5月收治的104例反流性食管炎患者作为研究对象，随机分为观察组和对照组，各组52例。对照组给予常规西药治疗，观察组在对照组的基础上联合中药疏肝和胃降逆汤治疗，比较两组治疗前后的胃镜积分、症状积分、治疗后的临床效果及半年复发率。结果两组治疗后的胃镜积分、症状积分显著低于治疗前，差异有统计学意义(P<0.01)。观察组治疗后的胃镜积分、症状积分显著低于对照组治疗后，差异有统计学意义(P<0.01)。观察组的总有效率为96.15%，显著高于对照组的65.38%，差异有统计学意义(P<0.05)。观察组的复发率为9.62%，显著低于对照组的48.08%，差异有统计学意义(P<0.01)。结论疏肝和胃降逆汤治疗反流性食管炎效果显著，能够降低患者的胃镜积分及症状积分，且复发率低，值得临床推广应用。
目的：探討疏肝和胃降逆湯治療反流性食管炎的效果。方法選取本院2012年1月~2014年5月收治的104例反流性食管炎患者作為研究對象，隨機分為觀察組和對照組，各組52例。對照組給予常規西藥治療，觀察組在對照組的基礎上聯閤中藥疏肝和胃降逆湯治療，比較兩組治療前後的胃鏡積分、癥狀積分、治療後的臨床效果及半年複髮率。結果兩組治療後的胃鏡積分、癥狀積分顯著低于治療前，差異有統計學意義(P<0.01)。觀察組治療後的胃鏡積分、癥狀積分顯著低于對照組治療後，差異有統計學意義(P<0.01)。觀察組的總有效率為96.15%，顯著高于對照組的65.38%，差異有統計學意義(P<0.05)。觀察組的複髮率為9.62%，顯著低于對照組的48.08%，差異有統計學意義(P<0.01)。結論疏肝和胃降逆湯治療反流性食管炎效果顯著，能夠降低患者的胃鏡積分及癥狀積分，且複髮率低，值得臨床推廣應用。
목적：탐토소간화위강역탕치료반류성식관염적효과。방법선취본원2012년1월~2014년5월수치적104례반류성식관염환자작위연구대상，수궤분위관찰조화대조조，각조52례。대조조급여상규서약치료，관찰조재대조조적기출상연합중약소간화위강역탕치료，비교량조치료전후적위경적분、증상적분、치료후적림상효과급반년복발솔。결과량조치료후적위경적분、증상적분현저저우치료전，차이유통계학의의(P<0.01)。관찰조치료후적위경적분、증상적분현저저우대조조치료후，차이유통계학의의(P<0.01)。관찰조적총유효솔위96.15%，현저고우대조조적65.38%，차이유통계학의의(P<0.05)。관찰조적복발솔위9.62%，현저저우대조조적48.08%，차이유통계학의의(P<0.01)。결론소간화위강역탕치료반류성식관염효과현저，능구강저환자적위경적분급증상적분，차복발솔저，치득림상추엄응용。
Objective To explore the effect of Shugan Hewei Jiangni decoction in the treatment of reflux esophagitis. Methods 104 patients with reflux esophagitis from January 2012 to May 2014 in our hospital were selected and randomly divided into the observation group and the control group,52 cases in each group.The control group was given regular treatment of western medicine,the observation group was given Shugan Hewei Jiangni decoction on the basis of the control group.Gastroscopic score,symptom score,clinical curative effect after treatment and half-year relapse rate in two groups before and after treatment was compared respectively. Results Gastroscopic score and symptoms score in two groups after treatment was lower than that before treatment,with significant difference (P<0.01).Gastroscopic score and symptoms score in the observation group after treatment was lower than that in the control group after treatment, with significant difference (P<0.01).The total effective rate in the observation group was 96.15%,which was higher than 65.38% in the control group,with significant difference (P<0.05).The relapse rate in the observation group was 9.62%, which was lower than 48.08% in the control group,with significant difference(P<0.01). Conclusion The effect of Shugan Hewei Jiangni decoction in the treatment of reflux esophagitis is significant,which can reduce gastroscopic score and symptom score,and the relapse rate is low,it is worthy of clinical promotion and application.
