中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
17期
120-122
,共3页
细菌耐药性%病原菌%抗菌药物%分析
細菌耐藥性%病原菌%抗菌藥物%分析
세균내약성%병원균%항균약물%분석
Bacterial drug resistance%Pathogen%Antimicrobial agents%Analysis
目的：分析本院2014年1~12月的临床细菌分布及耐药性，为临床合理应用抗菌药物提供参考依据。方法回顾性分析本院2014年临床病原菌分布及耐药情况，采用WHONET 5.6软件统计分析。结果全年共分离出病原菌1698株，其中革兰氏阴性杆菌占64.9%，非发酵菌占8.8%，革兰氏阳性球菌占26.3%。肠杆菌科常见的大肠埃希菌、肺炎克雷伯菌、产酸克雷伯菌对哌拉西林他唑巴坦、头孢哌酮舒巴坦、碳青霉烯类的耐药率较低，非发酵菌铜绿假单胞菌对哌拉西林他唑巴坦、三代头孢的耐药率低，鲍曼不动杆菌对大多数抗菌药物的耐药率均较高，未发现对万古霉素耐药的葡萄球菌属和肠球菌属。结论监测结果对临床正确合理地应用抗菌药物、降低细菌耐药有积极意义。
目的：分析本院2014年1~12月的臨床細菌分佈及耐藥性，為臨床閤理應用抗菌藥物提供參攷依據。方法迴顧性分析本院2014年臨床病原菌分佈及耐藥情況，採用WHONET 5.6軟件統計分析。結果全年共分離齣病原菌1698株，其中革蘭氏陰性桿菌佔64.9%，非髮酵菌佔8.8%，革蘭氏暘性毬菌佔26.3%。腸桿菌科常見的大腸埃希菌、肺炎剋雷伯菌、產痠剋雷伯菌對哌拉西林他唑巴坦、頭孢哌酮舒巴坦、碳青黴烯類的耐藥率較低，非髮酵菌銅綠假單胞菌對哌拉西林他唑巴坦、三代頭孢的耐藥率低，鮑曼不動桿菌對大多數抗菌藥物的耐藥率均較高，未髮現對萬古黴素耐藥的葡萄毬菌屬和腸毬菌屬。結論鑑測結果對臨床正確閤理地應用抗菌藥物、降低細菌耐藥有積極意義。
목적：분석본원2014년1~12월적림상세균분포급내약성，위림상합리응용항균약물제공삼고의거。방법회고성분석본원2014년림상병원균분포급내약정황，채용WHONET 5.6연건통계분석。결과전년공분리출병원균1698주，기중혁란씨음성간균점64.9%，비발효균점8.8%，혁란씨양성구균점26.3%。장간균과상견적대장애희균、폐염극뢰백균、산산극뢰백균대고랍서림타서파탄、두포고동서파탄、탄청매희류적내약솔교저，비발효균동록가단포균대고랍서림타서파탄、삼대두포적내약솔저，포만불동간균대대다수항균약물적내약솔균교고，미발현대만고매소내약적포도구균속화장구균속。결론감측결과대림상정학합리지응용항균약물、강저세균내약유적겁의의。
Objective To analyze the change of bacterial distribution and resistance in our hospital from January to De-cember in 2014, and provide reference basis for clinical rational using of antibiotics. Methods Clinical pathogenic bacteria distribution and drug resistance in 2014 in our hospital were retrospectively analyzed by statistical analysis of WHONET5.6 software. Results There were 1698 strains of pathogens isolated in full-year, of which Gram-negative bacilli was 64.9%,non-fermenting bacteria was 8.8%, and Gram-positive cocci was 26.3%.Enterobacteriaceae common-ly seen as escherichia coli,Klebsiella pneumoniae and Klebsiella oxytocahad lower resistance rates to piperacillin tazobactam,cefoperazone sulbactam,and carbapenem.Pseudomonas aeruginosa of non-fermenting bacterium had lower resistance to piperacillin tazobactam and third generation cephalosporins.Acinetobacter baumannii had a higher resis-tance to most antibacterial agents.Staphylococcus and Enterococcus resisting on vancomycin was not detected. Con-clusion Monitoring results play positive meanings in proper and rational use of antimicrobial agents in clinic and de-crease of bacterial resistance.
