中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2015年
18期
38-39
,共2页
脑血栓%阿片受体拮抗剂%神经功能缺损
腦血栓%阿片受體拮抗劑%神經功能缺損
뇌혈전%아편수체길항제%신경공능결손
Cerebral thrombus%Opioid receptor antagonist%Nerve function defect
目的：研究脑血栓应用阿片受体拮抗剂的临床疗效。方法：对照组在基础治疗基础上应用复方丹参注射液，治疗组在基础治疗基础上应用阿片受体拮抗剂代表药物盐酸纳洛酮注射液。治疗结束后比较两组疗效、起效时间、神经功能变化情况。结果：治疗组总有效率90.6%，显著高于对照组的79.3%（P＜0.05）。治疗组药物起效时间显著优于对照组（P＜0.05）。两组治疗前NIHSS评分无显著差异（P＞0.05），治疗后均显著好于治疗前（P＜0.05），治疗组神经功能恢复幅度显著优于对照组（P＜0.05）。两组治疗期间均无显著不良反应诱发。结论：脑血栓应用阿片受体拮抗剂疗效确切，安全性好。
目的：研究腦血栓應用阿片受體拮抗劑的臨床療效。方法：對照組在基礎治療基礎上應用複方丹參註射液，治療組在基礎治療基礎上應用阿片受體拮抗劑代錶藥物鹽痠納洛酮註射液。治療結束後比較兩組療效、起效時間、神經功能變化情況。結果：治療組總有效率90.6%，顯著高于對照組的79.3%（P＜0.05）。治療組藥物起效時間顯著優于對照組（P＜0.05）。兩組治療前NIHSS評分無顯著差異（P＞0.05），治療後均顯著好于治療前（P＜0.05），治療組神經功能恢複幅度顯著優于對照組（P＜0.05）。兩組治療期間均無顯著不良反應誘髮。結論：腦血栓應用阿片受體拮抗劑療效確切，安全性好。
목적：연구뇌혈전응용아편수체길항제적림상료효。방법：대조조재기출치료기출상응용복방단삼주사액，치료조재기출치료기출상응용아편수체길항제대표약물염산납락동주사액。치료결속후비교량조료효、기효시간、신경공능변화정황。결과：치료조총유효솔90.6%，현저고우대조조적79.3%（P＜0.05）。치료조약물기효시간현저우우대조조（P＜0.05）。량조치료전NIHSS평분무현저차이（P＞0.05），치료후균현저호우치료전（P＜0.05），치료조신경공능회복폭도현저우우대조조（P＜0.05）。량조치료기간균무현저불량반응유발。결론：뇌혈전응용아편수체길항제료효학절，안전성호。
Objective:To study clinical effect of opioid receptor antagonist on cerebral thrombosis. Methods:the control group was treated with Compound Danshen Injection more than basic treatment, and the research group was treated with opioid antagonists.After the treatment, the effect,the onset time and the nerve function in the two groups were compared.Results:the total efficiency in the study group was 79.25%,significantly higher than that in the control group (P<0.05). Clinical effect in the study group was significantly better (P <0.05).The score of NIHSS before treatment was not significantly different before treatment (P<0.05),and the recovery of neurological function in the study group was significantly better than that in the control group (P<0.05), after treatment. No significant adverse reactions were induced in the two groups. Conclusion:Clinical effects of opioid receptor antagonist is effective and safe in cerebral thrombosis.
