中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
17期
52-54
,共3页
解剖性肝切除术%非解剖性肝切除术%晚期肝癌%安全性%临床疗效
解剖性肝切除術%非解剖性肝切除術%晚期肝癌%安全性%臨床療效
해부성간절제술%비해부성간절제술%만기간암%안전성%림상료효
Anatomic hepatectomy%Non anatomic hepatectomy%Advanced liver cancer%Security%Clinical curative effect
目的：比较解剖性与非解剖性肝切除术治疗晚期肝癌的临床效果。方法选取南阳医专一附：2011年1月~2013年6月行手术治疗的98例晚期肝癌患者作为研究对象。根据手术方式，将患者分为观察组和对照组。观察组(n=59)采用解剖性肝切除术，对照组(n=39)采用非解剖性肝切除术。比较两组的术中、术后相关指标。结果术中相关指标：观察组的手术时间为(271.5±97.4)min，长于对照组的(188.5±70.7)min，切缘有效率为89.8%，明显高于对照组的53.8%，差异有统计学意义(P<0.05)；两组的术中出血量、术中输血量比较，差异无统计学意义(P>0.05)。术后相关指标：观察组术后3 d血清ALT值为(270.5±94.1)U/L，显著低于对照组的(501.6±115.6)U/L；观察组术后1年复发率明显低于对照组，术后1年生存率明显高于对照组(P<0.05)。结论对于有手术切除指征的晚期肝癌患者，解剖性肝切除术具有更高的安全性与临床疗效，值得临床推广应用。
目的：比較解剖性與非解剖性肝切除術治療晚期肝癌的臨床效果。方法選取南暘醫專一附：2011年1月~2013年6月行手術治療的98例晚期肝癌患者作為研究對象。根據手術方式，將患者分為觀察組和對照組。觀察組(n=59)採用解剖性肝切除術，對照組(n=39)採用非解剖性肝切除術。比較兩組的術中、術後相關指標。結果術中相關指標：觀察組的手術時間為(271.5±97.4)min，長于對照組的(188.5±70.7)min，切緣有效率為89.8%，明顯高于對照組的53.8%，差異有統計學意義(P<0.05)；兩組的術中齣血量、術中輸血量比較，差異無統計學意義(P>0.05)。術後相關指標：觀察組術後3 d血清ALT值為(270.5±94.1)U/L，顯著低于對照組的(501.6±115.6)U/L；觀察組術後1年複髮率明顯低于對照組，術後1年生存率明顯高于對照組(P<0.05)。結論對于有手術切除指徵的晚期肝癌患者，解剖性肝切除術具有更高的安全性與臨床療效，值得臨床推廣應用。
목적：비교해부성여비해부성간절제술치료만기간암적림상효과。방법선취남양의전일부：2011년1월~2013년6월행수술치료적98례만기간암환자작위연구대상。근거수술방식，장환자분위관찰조화대조조。관찰조(n=59)채용해부성간절제술，대조조(n=39)채용비해부성간절제술。비교량조적술중、술후상관지표。결과술중상관지표：관찰조적수술시간위(271.5±97.4)min，장우대조조적(188.5±70.7)min，절연유효솔위89.8%，명현고우대조조적53.8%，차이유통계학의의(P<0.05)；량조적술중출혈량、술중수혈량비교，차이무통계학의의(P>0.05)。술후상관지표：관찰조술후3 d혈청ALT치위(270.5±94.1)U/L，현저저우대조조적(501.6±115.6)U/L；관찰조술후1년복발솔명현저우대조조，술후1년생존솔명현고우대조조(P<0.05)。결론대우유수술절제지정적만기간암환자，해부성간절제술구유경고적안전성여림상료효，치득림상추엄응용。
Objective To compare the clinical effect of anatomic and non anatomic hepatectomy treating advanced liver carcinoma. Methods 98 patients with advanced liver cancer treated by surgery in the First Affiliated Hospital of Nanyang Medical College from January 2011 to June 2013 were selected as study objects.According to operation method,they were divided into observation group and control group,the observation group (n=59) was given anatomic hepatectomy,while control group (n=39) was given non anatomical hepatectomy, intraoperative and postoperative related indicators between two groups was compared respectively. Results Intraoperative and postoperative related indicators:operating time of observation group [(271.5+97.4) min] was longer than that of control group [(188.5+70.7) min],effective rate of cutting edge of observation group (89.8%) was obviously higher than that of control group (53.8%),and there was a statistical difference (P<0.05);there was no statistical difference of intraoperative blood loss and blood transfusion amount between two groups (P>0.05).Postoperative related indicators:serum ALT value after 3 days operation in obser-vation group [(270.5+94.1) U/L] was obviously lower than that of control group [(501.6+115.6) U/L],and recurrence rate after 1 year operation in observation group was obviously lower than that of control group,survival rate after 1 year oper-ation in observation group was obviously higher than that of control group (P<0.05). Conclusion For patients with ad-vanced liver cancer with surgical removal of indication,anatomic hepatectomy has higher safety and clinical efficacy.It is worthy of clinical promotion and application.
