CAJ | 학술논문

目的：分析门静脉高压症术后抗凝治疗下门静脉血栓形成的危险因素。方法回顾性分析我院门静脉高压症手术治疗的96例患者的临床资料。分为血栓组和非血栓组，对可能预测门静脉血栓形成的各种因素进行分析。结果96例患者中有41例(40.08%)出现门静脉血栓。患者性别、年龄、Child-Pugh 分级、手术方式、手术前后门静脉压力及压力差、凝血酶原时间、术前血小板计数、脾脏指数、门静脉内径等均不是预测门静脉血栓形成的危险因素；脾静脉直径是门静脉血栓形成的独立危险因素(P =0.036)，当脾静脉直径>11 mm 时，术后容易形成门静脉血栓。结论术前彩色多普勒检测脾静脉直径可以预测门静脉高压症患者手术治疗后门静脉血栓形成。
목적：분석문정맥고압증술후항응치료하문정맥혈전형성적위험인소。방법회고성분석아원문정맥고압증수술치료적96례환자적림상자료。분위혈전조화비혈전조，대가능예측문정맥혈전형성적각충인소진행분석。결과96례환자중유41례(40.08%)출현문정맥혈전。환자성별、년령、Child-Pugh 분급、수술방식、수술전후문정맥압력급압력차、응혈매원시간、술전혈소판계수、비장지수、문정맥내경등균불시예측문정맥혈전형성적위험인소；비정맥직경시문정맥혈전형성적독립위험인소(P =0.036)，당비정맥직경>11 mm 시，술후용역형성문정맥혈전。결론술전채색다보륵검측비정맥직경가이예측문정맥고압증환자수술치료후문정맥혈전형성。
Objective To investigate the risk factors for portal vein thrombosis (PVT)under anticoagulation therapy after surgery in patients with portal hypertension.Methods We made a retrospective analysis of clinical data of 96 portal hypertension patients for surgical treatment at our hospital.All the patients with postoperative PVT or without were divided into two groups.Risk factors that may predict PVT were analyzed.Results PVT developed in 41 (40.08%)of 96 patients after surgery.Risk factors such as sex,age,Child-Pugh classification,type of operation,portal pressure and the pressure difference before and after surgery,preoperative prothrombin time, preoperative platelet count,spleen index,and portal vein diameter were not predictors of PVT.However,splenic vein diameter was an independent risk factor for PVT (P = 0.036);postoperative PVT tended to develop when the splenic vein diameter was larger than 1 1 mm.Conclusion Preoperative color Doppler testing of splenic vein diameter can predict PVT after surgery in patients with portal hypertension.