CAJ | 학술논문

目的：观察低压无针注射联合硅胶膜治疗瘢痕疙瘩的临床疗效。方法：将198例瘢痕疙瘩患者随机分为三组。对照组：65例，采用普通注射器向瘢痕内注射曲安奈德治疗,每2周1次，连续8次；治疗1组：67例，采用低压无针注射仪向瘢痕内注射曲安奈德治疗；治疗2组：66例，在治疗1组治疗的基础上辅以硅胶膜敷料继续治疗至随访期结束。疗程为16周，随访期为6个月，观察三组患者的有效率、复发率、安全性和治疗中的疼痛程度。结果：对照组有效率49.23%，复发率16.92%，治疗1组有效率为70.15%，复发率为7.46%，治疗2组有效率为72.73%，复发率为1.52%，治疗组有效率明显高于对照组（P＜0.05），治疗2组的复发率明显低于对照组（P＜0.01）；对照组的疼痛评分为6.12±0.27，治疗1、2组分别为3.19±0.23，3.36±0.28，治疗组的疼痛评分明显低于对照组（P＜0.01）。结论：低压无针注射联合硅胶膜治疗瘢痕疙瘩疗效好，复发率低，值得临床推广应用。
목적：관찰저압무침주사연합규효막치료반흔흘탑적림상료효。방법：장198례반흔흘탑환자수궤분위삼조。대조조：65례，채용보통주사기향반흔내주사곡안내덕치료,매2주1차，련속8차；치료1조：67례，채용저압무침주사의향반흔내주사곡안내덕치료；치료2조：66례，재치료1조치료적기출상보이규효막부료계속치료지수방기결속。료정위16주，수방기위6개월，관찰삼조환자적유효솔、복발솔、안전성화치료중적동통정도。결과：대조조유효솔49.23%，복발솔16.92%，치료1조유효솔위70.15%，복발솔위7.46%，치료2조유효솔위72.73%，복발솔위1.52%，치료조유효솔명현고우대조조（P＜0.05），치료2조적복발솔명현저우대조조（P＜0.01）；대조조적동통평분위6.12±0.27，치료1、2조분별위3.19±0.23，3.36±0.28，치료조적동통평분명현저우대조조（P＜0.01）。결론：저압무침주사연합규효막치료반흔흘탑료효호，복발솔저，치득림상추엄응용。
Objective To observe the clinical efficacy of needle free jet injector and silicone dressing in the treatment of keloid. Methods The selected 198 cases of patients with keloid were divided into three groups randomly.The control group of 65 cases,received intralesional injection of triamcinolone acetonide by ordinary injector once every two weeks for 16 weeks.Treatment group 1 of 67 cases,received intralesional injection of triamcinolone acetonide by needle free jet injector.Treatment group 2 of 66 cases were increased by silicone dressing for 6 months.Three groups were observed in the effective rate,recurrence rate,safety and the pain during the treatment. Results The effective rate of control group was 49.23%, the recurrence rate was 16.92.The effective rate of the treatment group 1 was 70.15%,the recurrence rate was 7.46%.The effective rate of treatment group 2 was 72.73%,the recurrence rate was 1.52%.The effective rate of the treatment groups were significantly higher than that of the control group (P<0.05). The recurrence rate of treatment group 2 was lower than that of control group (P<0.01).The pain scores of control group was (6.12±0.27).The treatment group 1 was (3.19 ± 0.23) and the treatment group 2 was (3.36 ± 0.28).The pain scores of treatment groups were significantly lower than the control group (P<0.01). Conclusion Combined intralesional injection of triamcinolone acetonide by needle free jet injector and silicone dressing is an effective method for treatment of keloid with low recurrence rate,and is worthy of clinical doctors to select.