中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
18期
119-121
,共3页
系统性红斑狼疮%干眼%眼表
繫統性紅斑狼瘡%榦眼%眼錶
계통성홍반랑창%간안%안표
Systemic lupus erythematosus%Dry eye%Ocular surface
目的：探讨系统性红斑狼疮（SLE）患者眼表状态的临床特点。方法：选择本院2014年4-12月住院并经风湿免疫科医生确诊为系统性红斑狼疮的患者26例作为SLE组，同时选择眼科门诊非系统性红斑狼疮患者20例作为对照组，通过角膜荧光素染色、SchimerⅠ试验及泪膜破裂时间测定比较两组眼表状态的差异。结果：SLE组BUT明显短于对照组，差异有统计学意义（t=2.673，P<0.01）。SLE组与对照组比较，泪液分泌量减少，差异有统计学意义（t=2.62，P<0.05）。SLE患者角膜荧光素染色检出率高于对照组，差异有统计学意义（u=2.46，P<0.01）。结论：系统性红斑狼疮患者容易出现眼表状态的异常改变，是干眼症的易患人群；角膜荧光素染色、SchimerⅠ试验及泪膜破裂时间有助于发现SLE患者眼表状态的异常改变。
目的：探討繫統性紅斑狼瘡（SLE）患者眼錶狀態的臨床特點。方法：選擇本院2014年4-12月住院併經風濕免疫科醫生確診為繫統性紅斑狼瘡的患者26例作為SLE組，同時選擇眼科門診非繫統性紅斑狼瘡患者20例作為對照組，通過角膜熒光素染色、SchimerⅠ試驗及淚膜破裂時間測定比較兩組眼錶狀態的差異。結果：SLE組BUT明顯短于對照組，差異有統計學意義（t=2.673，P<0.01）。SLE組與對照組比較，淚液分泌量減少，差異有統計學意義（t=2.62，P<0.05）。SLE患者角膜熒光素染色檢齣率高于對照組，差異有統計學意義（u=2.46，P<0.01）。結論：繫統性紅斑狼瘡患者容易齣現眼錶狀態的異常改變，是榦眼癥的易患人群；角膜熒光素染色、SchimerⅠ試驗及淚膜破裂時間有助于髮現SLE患者眼錶狀態的異常改變。
목적：탐토계통성홍반랑창（SLE）환자안표상태적림상특점。방법：선택본원2014년4-12월주원병경풍습면역과의생학진위계통성홍반랑창적환자26례작위SLE조，동시선택안과문진비계통성홍반랑창환자20례작위대조조，통과각막형광소염색、SchimerⅠ시험급루막파렬시간측정비교량조안표상태적차이。결과：SLE조BUT명현단우대조조，차이유통계학의의（t=2.673，P<0.01）。SLE조여대조조비교，루액분비량감소，차이유통계학의의（t=2.62，P<0.05）。SLE환자각막형광소염색검출솔고우대조조，차이유통계학의의（u=2.46，P<0.01）。결론：계통성홍반랑창환자용역출현안표상태적이상개변，시간안증적역환인군；각막형광소염색、SchimerⅠ시험급루막파렬시간유조우발현SLE환자안표상태적이상개변。
Objective:To explore the ocular surface manifestations of systemic lupus erythematosus patients.Method:26 patients who were confirmed with systemic lupus erythematosus in our hospital from April 2014 to December 2014 were selected as the SLE group,20 patients from the ophthalmology clinic outpatient who had no systemic lupus erythematosus were selected as the control group.The ocular surface manifestations of the SLE patients was compared with that of the control group(20 cases) through cornea fluorescein staining,Schirmer test and test of tear film breaking up time.Result:Compared with the control group, the mean BUT of the SLE group was significantly shorter(t=2.62,P<0.05),the value of Schirmer Ⅰ test of the SLE group was significantly lower(t=2.62,P<0.05)and the positive rate of cornea fluorescein staining of the SLE group was significantly higher.Conclusion:Patients with systemic lupus erythematosus show a tendency to have changes of ocular surface state.They are susceptible population of dry eyes.Corneal fluorescein staining,Schimer Ⅰ test and tear film breaking up time test help to find abnormal changes of ocular surface state of SLE patients.
