中国肿瘤临床
中國腫瘤臨床
중국종류림상
CHINESE JOURNAL OF CLINICAL ONCOLOGY
2015年
12期
603-607
,共5页
李虹义%魏振军(综述)%刘端祺(审校)
李虹義%魏振軍(綜述)%劉耑祺(審校)
리홍의%위진군(종술)%류단기(심교)
阿片类药物%镇痛药%便秘%诊断%治疗流程
阿片類藥物%鎮痛藥%便祕%診斷%治療流程
아편류약물%진통약%편비%진단%치료류정
opioid%analgesics%constipation%diagnosis%treatment process
阿片类药物相关性便秘(opioid-induced constipation,OIC)是阿片类药物应用过程中最常见的不良反应,其困扰着癌痛患者和医务工作者,影响癌痛患者的疼痛控制。因此,控制OIC则显得十分必要。但是关于OIC的诊断未达成共识,有必要探讨与统一其诊断,以便交流和比较治疗效果。本研究提出了OIC相关的诊断意见并概述了OIC治疗,包括药物治疗和非药物治疗;同时提出OIC预防、治疗的初步流程,以利于临床工作者方便使用。
阿片類藥物相關性便祕(opioid-induced constipation,OIC)是阿片類藥物應用過程中最常見的不良反應,其睏擾著癌痛患者和醫務工作者,影響癌痛患者的疼痛控製。因此,控製OIC則顯得十分必要。但是關于OIC的診斷未達成共識,有必要探討與統一其診斷,以便交流和比較治療效果。本研究提齣瞭OIC相關的診斷意見併概述瞭OIC治療,包括藥物治療和非藥物治療;同時提齣OIC預防、治療的初步流程,以利于臨床工作者方便使用。
아편류약물상관성편비(opioid-induced constipation,OIC)시아편류약물응용과정중최상견적불량반응,기곤우착암통환자화의무공작자,영향암통환자적동통공제。인차,공제OIC칙현득십분필요。단시관우OIC적진단미체성공식,유필요탐토여통일기진단,이편교류화비교치료효과。본연구제출료OIC상관적진단의견병개술료OIC치료,포괄약물치료화비약물치료;동시제출OIC예방、치료적초보류정,이리우림상공작자방편사용。
Opioid-induced constipation (OIC) is the most common side effect of opioid. OIC influences the quality of life of pa-tients suffering from cancer pain. However, given that the drug is often overlooked and underappreciated, most of the time, the patients would avoid or abandon using opioid and, as a result, they continuously suffer from cancer pain. Therefore, OIC prevention and man-agement must be made before opioid use. The consensus on the diagnosis of OIC has only been reached recently. Thus, a unified defini-tion of OIC must be developed to exchange therapeutic option among departments in hospitals and compare treatment outcome. The di-agnosis of OIC is discussed, and the management of OIC, including medicinal and non-medicinal treatment, is summarized. Mean-while, the initial program for prevention and treatment of OIC is established to make OIC management more convenient for clinical physicians. Much work is still needed to establish a consensus on OIC diagnosis and a suitable program for prevention and treatment of OIC.