CAJ | 학술논문

目的：探讨用消散外敷预防保守性微创术联合米非司酮治疗输卵管妊娠后持续性异位妊娠（PEP）的治疗效果。方法：对104例确诊为输卵管妊娠的患者行保守性治疗联合米非司酮保守治疗，随机分为2组，实验组52例予以保守性手术＋米非司酮口服，术后加用中药《消散》外敷；对照组52例，予以保守性手术＋米非司酮口服。结果：对照组中有2例发生 PEP，实验组在 PEP 发生率治愈成功率、血β－HCG 降至正常所用时间、患侧输卵管复通率等方面均明显优于对照组（P ＜0.05）.结论：术后加用中药《消散》外敷能成功预防保守性微创术治疗输卵管妊娠后 PEP 的发生，避免术前因为警惕 PEP 发生而对病例进行筛查，扩大了保守性手术治疗的范围。而且还最大限度地保留了输卵管组织的完整性，减轻了患者的痛苦，消散外敷在保守性微创术联合米非司酮治疗输卵管妊娠有推广价值。
목적：탐토용소산외부예방보수성미창술연합미비사동치료수란관임신후지속성이위임신（PEP）적치료효과。방법：대104례학진위수란관임신적환자행보수성치료연합미비사동보수치료，수궤분위2조，실험조52례여이보수성수술＋미비사동구복，술후가용중약《소산》외부；대조조52례，여이보수성수술＋미비사동구복。결과：대조조중유2례발생 PEP，실험조재 PEP 발생솔치유성공솔、혈β－HCG 강지정상소용시간、환측수란관복통솔등방면균명현우우대조조（P ＜0.05）.결론：술후가용중약《소산》외부능성공예방보수성미창술치료수란관임신후 PEP 적발생，피면술전인위경척 PEP 발생이대병례진행사사，확대료보수성수술치료적범위。이차환최대한도지보류료수란관조직적완정성，감경료환자적통고，소산외부재보수성미창술연합미비사동치료수란관임신유추엄개치。
Objective:To investigate the effect of XIAOZHENGSAN external application in the conservative minimally invasive surgery combined with mife-pristone to preventing and curing persistent ectopic pregnancy after tubal pregnancy Methods:Having conservative minimally invasive surgery for 104 patients di-agnosed as tubal pregnancy,and randomly divided them into two groups.Experimental group include 52 patients who have had this kind of surgery and oral mife-pristone,XIAOZHENGSAN applied externally after the surgery.Comparison group include the other 52 patients who just have taken the conservative minimally invasive surgery and oral mifepristone.Result:Two cases of PEP occurred in the comparison group,the two groups were significantly different (P <0.05),the performance of experimental group was obviously better than the comparison group (P <0.05),especially in the aspects of the PEP incidence,recovery time of the serum β-HCG and the ipsilateral fallopian tube recanalization rate.Conclusion:Preoperative and postoperative oral mifepristone and externally application of XIAOZHENGSAN after the operation will be extremely effective to preventing the PEP occurrence from a conservative minimally invasive surgery for tubal preg-nancy,avoiding the unnecessary screening for patients who are at risk from PEP,and expanded the range of conservative surgical treatment.More importantly, it maximized the opportunity of oviduct tissue integrity,and improved the success rate of conservative surgery.External application of XIAOZHENGSAN is worth popularizing in the field of the conservative minimally invasive surgery combined with mifepristone to preventing and curing the persistent ectopic pregnancy.