中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
18期
8-10,11
,共4页
陈锋%彭慕立%梁国华%彭秉纲
陳鋒%彭慕立%樑國華%彭秉綱
진봉%팽모립%량국화%팽병강
OCSP%脑梗死%急性期%血压调控%预后
OCSP%腦梗死%急性期%血壓調控%預後
OCSP%뇌경사%급성기%혈압조공%예후
OCSP%Cerebral infarction%Acute phase%Blood pressure regulation%Prognosis
目的：探讨不同类型脑梗死患者急性期血压调控对预后的影响。方法：将162例脑梗死急性期患者随机分为对照组（n=95）与干预组（n=67），对照组患者均常规应用阿司匹林、钙拮抗剂，并辅以胞二磷胆碱进行对症支持性治疗，干预组在对照组基础上采用药物进行降血压治疗，使患者入院1 d内的血压下降至160/100 mm Hg内，采用NIHSS评分、Barthel Index评分及改良Rankin评分比较两组患者入院时、治疗第1周、治疗半年及治疗1年时的评分情况。结果：干预组治疗第1周的Barthel Index评分为（46.3±12.8）分，显著低于对照组的（49.1±13.3）分，差异有统计学意义（P<0.05）；干预组治疗半年及1年后的NIHSS评分、Barthel Index评分及改良Rankin评分显著低于对照组同期水平（P<0.05或P<0.01）；干预组治疗1周后的TACI、PACI、POCI型Barthel Index评分均显著低于对照组水平（P<0.05）；治疗1周后TACI型的改良Rankin显著高于对照组（P<0.05）；治疗半年后LACI、TACI、PACI、POCI的Barthel Index评分显著低于对照组（P<0.05或P<0.01）；治疗半年后TACI、PACI型的NIHSS评分显著高于对照组（P<0.05或P<0.01）。结论：脑梗死急性期早期进行降血压治疗预后效果往往不良。
目的：探討不同類型腦梗死患者急性期血壓調控對預後的影響。方法：將162例腦梗死急性期患者隨機分為對照組（n=95）與榦預組（n=67），對照組患者均常規應用阿司匹林、鈣拮抗劑，併輔以胞二燐膽堿進行對癥支持性治療，榦預組在對照組基礎上採用藥物進行降血壓治療，使患者入院1 d內的血壓下降至160/100 mm Hg內，採用NIHSS評分、Barthel Index評分及改良Rankin評分比較兩組患者入院時、治療第1週、治療半年及治療1年時的評分情況。結果：榦預組治療第1週的Barthel Index評分為（46.3±12.8）分，顯著低于對照組的（49.1±13.3）分，差異有統計學意義（P<0.05）；榦預組治療半年及1年後的NIHSS評分、Barthel Index評分及改良Rankin評分顯著低于對照組同期水平（P<0.05或P<0.01）；榦預組治療1週後的TACI、PACI、POCI型Barthel Index評分均顯著低于對照組水平（P<0.05）；治療1週後TACI型的改良Rankin顯著高于對照組（P<0.05）；治療半年後LACI、TACI、PACI、POCI的Barthel Index評分顯著低于對照組（P<0.05或P<0.01）；治療半年後TACI、PACI型的NIHSS評分顯著高于對照組（P<0.05或P<0.01）。結論：腦梗死急性期早期進行降血壓治療預後效果往往不良。
목적：탐토불동류형뇌경사환자급성기혈압조공대예후적영향。방법：장162례뇌경사급성기환자수궤분위대조조（n=95）여간예조（n=67），대조조환자균상규응용아사필림、개길항제，병보이포이린담감진행대증지지성치료，간예조재대조조기출상채용약물진행강혈압치료，사환자입원1 d내적혈압하강지160/100 mm Hg내，채용NIHSS평분、Barthel Index평분급개량Rankin평분비교량조환자입원시、치료제1주、치료반년급치료1년시적평분정황。결과：간예조치료제1주적Barthel Index평분위（46.3±12.8）분，현저저우대조조적（49.1±13.3）분，차이유통계학의의（P<0.05）；간예조치료반년급1년후적NIHSS평분、Barthel Index평분급개량Rankin평분현저저우대조조동기수평（P<0.05혹P<0.01）；간예조치료1주후적TACI、PACI、POCI형Barthel Index평분균현저저우대조조수평（P<0.05）；치료1주후TACI형적개량Rankin현저고우대조조（P<0.05）；치료반년후LACI、TACI、PACI、POCI적Barthel Index평분현저저우대조조（P<0.05혹P<0.01）；치료반년후TACI、PACI형적NIHSS평분현저고우대조조（P<0.05혹P<0.01）。결론：뇌경사급성기조기진행강혈압치료예후효과왕왕불량。
Objective:To explore the efficacy of acute blood pressure regulation in different types cerebral infarction prognosis.Method:162 patients with acute cerebral infarction were randomly divided into the control group(n=95) and the intervention group(n= 67).The control group patients patients were treated with routine use of aspirin,calcium antagonists, and supplemented citicoline be symptomatic and supportive treatment.The intervention group were treated with drugs for lowering blood pressure on the basis of the control group.Decreased blood pressure in 160/100 mm Hg in 1 day after admission.The NIHSS score,Barthel Index score and modified Rankin scores were compared at admission,the first week after treatment,six months after treatment and and 1 year after treatment between the two groups.Result:The Barthel Index score at the first week after treatment(46.3±12.8) points vs (49.1±13.3) points in the intervention group were significantly lower than the control group (P<0.05).The NIHSS,Barthel Index score and modified Rankin score at six months after treatment and 1 year after treatment in the intervention group were significantly lower than the same period of the control group(P<0.05 orP<0.01).The Barthel Index scores at the first week after treatment of TACI,PACI,POCI type were significantly lower than those of the control group (P<0.05).The modified Rankin score at the first week after treatment of TACI type was significantly higher than the control group (P<0.05).The Barthel Index scores at six months after treatment of LACI,TACI,PACI,POCI in the intervention group were significantly lower than the same period of the control group(P<0.05 orP<0.01).The NIHSS score at six months after treatment of LACI,TACI,PACI,POCI in the intervention group were significantly higher than the control group(P<0.05 orP<0.01). Conclusion:The efficacy of early Antihypertensive treat for acute cerebral infarction prognosis are poor.
