北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
7期
148-149,150
,共3页
治疗分析%临床诊断%围绝经期功能失调性子宫出血%米非司酮
治療分析%臨床診斷%圍絕經期功能失調性子宮齣血%米非司酮
치료분석%림상진단%위절경기공능실조성자궁출혈%미비사동
Treatment analysis%Clinical diagnosis%Perimenopausal dysfunctional uterine bleeding%Mifepristone
目的：探讨围绝经期功能失调性子宫出血的诊断及治疗分析。方法：选取我院2013年1月～2014年9月就诊妇科门诊的宫血患者112例，根据随机数字表法分为观察组和对照组，每组56例，观察组进行去氧孕烯炔雌醇片疗法，对照组进行地屈孕酮片疗法，两组均治疗6个月，停药后3个月随访，比较两组治疗后的临床效果、激素水平变化；评估两组患者治疗前后子宫内膜厚度情况。结果：观察组和对照组的临床有效率分别为62.5%和41.1%，差异有统计学意义（P<0.05）；两组治疗后的FH、E2、PRL、LH、孕酮等激素指标均有改善，但观察组治疗后的各项检查指标改善情况显著优于对照组（P<0.05）；两组治疗后子宫内膜厚度均有减低，观察组治疗后的子宫内膜厚度显著低于对照组，差异有统计学意义（P<0.05）。结论：围绝经期子宫内膜增厚的早期确诊十分重要，患者进行去氧孕烯炔雌醇片疗法，可显著改善患者的症状及激素水平，临床效果确切，值得临床推广。
目的：探討圍絕經期功能失調性子宮齣血的診斷及治療分析。方法：選取我院2013年1月～2014年9月就診婦科門診的宮血患者112例，根據隨機數字錶法分為觀察組和對照組，每組56例，觀察組進行去氧孕烯炔雌醇片療法，對照組進行地屈孕酮片療法，兩組均治療6箇月，停藥後3箇月隨訪，比較兩組治療後的臨床效果、激素水平變化；評估兩組患者治療前後子宮內膜厚度情況。結果：觀察組和對照組的臨床有效率分彆為62.5%和41.1%，差異有統計學意義（P<0.05）；兩組治療後的FH、E2、PRL、LH、孕酮等激素指標均有改善，但觀察組治療後的各項檢查指標改善情況顯著優于對照組（P<0.05）；兩組治療後子宮內膜厚度均有減低，觀察組治療後的子宮內膜厚度顯著低于對照組，差異有統計學意義（P<0.05）。結論：圍絕經期子宮內膜增厚的早期確診十分重要，患者進行去氧孕烯炔雌醇片療法，可顯著改善患者的癥狀及激素水平，臨床效果確切，值得臨床推廣。
목적：탐토위절경기공능실조성자궁출혈적진단급치료분석。방법：선취아원2013년1월～2014년9월취진부과문진적궁혈환자112례，근거수궤수자표법분위관찰조화대조조，매조56례，관찰조진행거양잉희결자순편요법，대조조진행지굴잉동편요법，량조균치료6개월，정약후3개월수방，비교량조치료후적림상효과、격소수평변화；평고량조환자치료전후자궁내막후도정황。결과：관찰조화대조조적림상유효솔분별위62.5%화41.1%，차이유통계학의의（P<0.05）；량조치료후적FH、E2、PRL、LH、잉동등격소지표균유개선，단관찰조치료후적각항검사지표개선정황현저우우대조조（P<0.05）；량조치료후자궁내막후도균유감저，관찰조치료후적자궁내막후도현저저우대조조，차이유통계학의의（P<0.05）。결론：위절경기자궁내막증후적조기학진십분중요，환자진행거양잉희결자순편요법，가현저개선환자적증상급격소수평，림상효과학절，치득림상추엄。
Objective: To investigate the diagnosis and treatment of perimenopausal functional uterine bleeding disorder analysis.Methods:60 cases of patients with perimenopausal dysfunctional uterine bleeding were selected in our hospital from September,2013 to September,2014, they were randomly divided into the observation group and control group, 30 cases in each group, the observation group were given mifepristone therapy, the control group were given pregnant three ketene therapy, two groups were treated for 6 months, after stopping drug 3 month follow-up of 6 months, changes in hormone levels, clinical effects were compared between the two groups after treatment of the two groups after treatment; evaluation of two groups of patients before and after endometrial thickness. Results: The clinical effective rate of the observation group and the control group, were 62.5% and 41.1%, the difference was statistically significant (P<0.05);FH, E2, PRL, LH, progesterone hormone indicators of the two group have improved after treatment, and the check index to improve the situation of the observation group after treatment were significantly better than the control group(P<0.05); the two groups after treatment were observed in endometrial thickness decreased, the thickness of endometrium group after treatment was significantly lower than that of the control group, the difference was statistically significant (P<0.05). Conclusion:Perimenopausal dysfunctional uterine bleeding in early diagnosis is very important, for patients with mifepristone therapy, can significantly improve the patient's symptoms and hormone levels, which had good clinical efficacy, it is worthy of clinical promotion.
