北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2015年
7期
146-147,148
,共3页
老年人%抗菌药物%药源性疾病
老年人%抗菌藥物%藥源性疾病
노년인%항균약물%약원성질병
Aged people%Antibacterial drug%Drug induced disease
目的：研究探讨老年人抗菌药物药源性疾病的规律及特点，为临床安全、合理应用抗菌药物提供依据。方法：对某院2006年2月～2014年3月间收治的老年人抗菌药物药源性疾病病例进行统计分析。结果：共收集病例136例，涉及该院38种抗菌药物。136例老年患者中，男性62例，女性74例；患者年龄最小63岁，最大96岁；按药物分类前3位分别为喹诺酮类（33例）、青霉素类（25例）、头孢菌素类（21例）；原发疾病涉及的主要系统以呼吸系统、消化系统、泌尿系统多见；药源性疾病发生时间在用药5d内患者较多，有96例（70.59%）；药源性疾病主要表现为过敏反应52例（38.24%），其次是毒性反应31例（22.79%）；发生率较多的给药途径为静脉滴注，有83例（61.03%）。结论：医护人员需重视老年人抗菌药物药源性疾病，合理应用抗菌药物并积极进行用药监护，为安全、有效的抗感染治疗提供依据。
目的：研究探討老年人抗菌藥物藥源性疾病的規律及特點，為臨床安全、閤理應用抗菌藥物提供依據。方法：對某院2006年2月～2014年3月間收治的老年人抗菌藥物藥源性疾病病例進行統計分析。結果：共收集病例136例，涉及該院38種抗菌藥物。136例老年患者中，男性62例，女性74例；患者年齡最小63歲，最大96歲；按藥物分類前3位分彆為喹諾酮類（33例）、青黴素類（25例）、頭孢菌素類（21例）；原髮疾病涉及的主要繫統以呼吸繫統、消化繫統、泌尿繫統多見；藥源性疾病髮生時間在用藥5d內患者較多，有96例（70.59%）；藥源性疾病主要錶現為過敏反應52例（38.24%），其次是毒性反應31例（22.79%）；髮生率較多的給藥途徑為靜脈滴註，有83例（61.03%）。結論：醫護人員需重視老年人抗菌藥物藥源性疾病，閤理應用抗菌藥物併積極進行用藥鑑護，為安全、有效的抗感染治療提供依據。
목적：연구탐토노년인항균약물약원성질병적규률급특점，위림상안전、합리응용항균약물제공의거。방법：대모원2006년2월～2014년3월간수치적노년인항균약물약원성질병병례진행통계분석。결과：공수집병례136례，섭급해원38충항균약물。136례노년환자중，남성62례，녀성74례；환자년령최소63세，최대96세；안약물분류전3위분별위규낙동류（33례）、청매소류（25례）、두포균소류（21례）；원발질병섭급적주요계통이호흡계통、소화계통、비뇨계통다견；약원성질병발생시간재용약5d내환자교다，유96례（70.59%）；약원성질병주요표현위과민반응52례（38.24%），기차시독성반응31례（22.79%）；발생솔교다적급약도경위정맥적주，유83례（61.03%）。결론：의호인원수중시노년인항균약물약원성질병，합리응용항균약물병적겁진행용약감호，위안전、유효적항감염치료제공의거。
Purpose To approach the regularity and characteristics of antibacterial drug induced disease of aged people , to apply antibacterial drug safely and reasonably. Method To statistical analysis the antibacterial drug induced disease of aged people in a certain hospital during February 2006 to March 2014. Result 136 cases were collected, including 38 antibacterial drugs in this hospital, including 62 male and 74 female; the youngest one is 63 years old, the oldest one is 96 years old; the first three categories of antibacterial drugs are quinolones(33 cases), penicillins(25 cases) and cephalosporins(21 cases); the most common systems involved in the primary disease are respiratory system, alimentary system and urinary system; the cases with the onset time of drug induced disease in 5 days is the most, with 96 cases (70.59%); the common manifestations of drug induced disease are allergic response(52 cases,38.24%),toxic reaction (31 cases, 22.79%);the most common administration route is intravenous drip, with 83 cases (61.03%) Conclusion Medical personnel should think highly of antibacterial drug induced disease of aged people , apply the antibacterial drug reasonably and monitor medication actively, to provide accordance with safe and effective anti-infective therapy.
