CAJ | 학술논문

目的：探讨右美托咪定在隆鼻术中应用的安全性与有效性。方法择期行隆鼻手术患者60例，随机等分为两组。静脉麻醉诱导后行局部麻醉。麻醉维持：D组应用0.5μg/(kg·h)右美托咪定至术毕前10 min，P组应用4 mg/(kg·h)丙泊酚至术毕。结果两组T0～T3的OAA/S评分和体动反应差异无统计学意义。与P组比较，D组辅助呼吸次数、芬太尼诱导时呛咳发生率降低，心动过缓发生率高(P＜0.05)。结论右美托咪定用于局部麻醉下行隆鼻手术的术中镇静能够达到丙泊酚的镇静强度，且安全性高。
목적：탐토우미탁미정재륭비술중응용적안전성여유효성。방법택기행륭비수술환자60례，수궤등분위량조。정맥마취유도후행국부마취。마취유지：D조응용0.5μg/(kg·h)우미탁미정지술필전10 min，P조응용4 mg/(kg·h)병박분지술필。결과량조T0～T3적OAA/S평분화체동반응차이무통계학의의。여P조비교，D조보조호흡차수、분태니유도시창해발생솔강저，심동과완발생솔고(P＜0.05)。결론우미탁미정용우국부마취하행륭비수술적술중진정능구체도병박분적진정강도，차안전성고。
Objective To explore the feasibility and safety of the application of dexm edetom idine to augm entation rhinoplasty.Methods 60 cases choosing to undergo augm entation rhinoplasty were random ly divided into 2 groups.Lo-cal anaesthesia was conducted after vein anesthesia induction .Maintenance of anesthesia:D exm edetom idine was infused at a rate of 0.5 μg/(kg·h)in group D until 10 m inutes before the end of surgery.Propofol was infused at a rate of 4 mg/(kg·h)in group P untilthe end ofsurgery.Results OAA/S score atT0~T3 and the body movementreaction in two groups had no difference of statistical significance.C om pared with group P ,assisted respiration frequency and fen-tanyl-induced cough occurrence rate in group D were low;bradycardia incidence in group D was high (P<0 .05 ). Con clusion D exm edetom idine for sedation under local anesthesia in augm entation rhinoplasty can achieve the strength of propofol sedation with high security.