CAJ | 학술논문

目的：进一步探究并分析血清同型半胱氨酸（HCY）同冠心病患者间的相关性以及其致病机理。方法：对过去一年（2014.1～2014.12）在我院内科门诊接受治疗的80例冠心病患者进行回顾研究，同时随机收集40例健康人员作为对照（NC组）。检测各组人员的血清HCY含量水平。结果：三种类型冠心病组患者血清HCY水平与健康人员比较均明显偏高，而且不同类型冠心病组患者间的血清HCY含量对比，也具有显著差异（P＜0.05）。同时，在单支、双支以及三支冠状动脉病变组中，血清HCY含量水平高低也差异明显，统计学意义显著（P＜0.05）。结论：血清HCY与人体冠心病病变情况密切相关，血清HCY含量水平的高低直接决定人体动脉粥样硬化程度，尤其对于早期冠状动脉粥样硬化，进行血清HCY检测能够有效判断患者冠心病动脉粥样硬化程度，可以及早进行预防与治疗。
목적：진일보탐구병분석혈청동형반광안산（HCY）동관심병환자간적상관성이급기치병궤리。방법：대과거일년（2014.1～2014.12）재아원내과문진접수치료적80례관심병환자진행회고연구，동시수궤수집40례건강인원작위대조（NC조）。검측각조인원적혈청HCY함량수평。결과：삼충류형관심병조환자혈청HCY수평여건강인원비교균명현편고，이차불동류형관심병조환자간적혈청HCY함량대비，야구유현저차이（P＜0.05）。동시，재단지、쌍지이급삼지관상동맥병변조중，혈청HCY함량수평고저야차이명현，통계학의의현저（P＜0.05）。결론：혈청HCY여인체관심병병변정황밀절상관，혈청HCY함량수평적고저직접결정인체동맥죽양경화정도，우기대우조기관상동맥죽양경화，진행혈청HCY검측능구유효판단환자관심병동맥죽양경화정도，가이급조진행예방여치료。
Objective: To explore and analyze the correlation between homocysteine and its pathogenesis of coronary heart disease in patients with the same type between serum. Methods: Over the past year (2014.2~2015.1) in my hospital outpatient treatment of 80cases of coronary heart disease were retrospectively studied, while a random collection of40 healthy people as controls (NC group). Serum HCY levels of each group staff. Results: Three types of CHD serum HCY levels compared to patients and health workers were significantly higher, and the content of serum HCY contrast between different types of patients with coronary heart disease, but also a significant difference (P<0.05). Meanwhile, in single, double and three coronary artery disease group, the serum levels of HCY level is also significantly different, statistically significant meaning (P<0.05). Conclusion: Serum HCY coronary heart disease is closely related to the human body, the serum levels of HCY level directly determines the degree of atherosclerosis in humans, especially for early coronary atherosclerosis, serum HCY can effectively detect patients with coronary atherosclerosis judge hardening can be prevented with early treatment.