CAJ | 학술논문

阿尔茨海默病（ AD）是引起老年痴呆最为常见的疾病，给我国及世界各国造成了严重的社会和经济负担。美国国家神经病及语言障碍和卒中研究所-阿尔茨海默氏病及相关疾病协会率先公布了AD的诊断标准。随着对AD认识的深入及新诊治技术的发展，AD的诊断标准也发生了较大改变，如更加重视对轻度认知功能障碍阶段的识别，以及在诊断标准中纳入生物标志物等，但不同标准之间也存在着较大的差异。因此，本文就AD诊断标准的演变做一综述。
아이자해묵병（ AD）시인기노년치태최위상견적질병，급아국급세계각국조성료엄중적사회화경제부담。미국국가신경병급어언장애화졸중연구소-아이자해묵씨병급상관질병협회솔선공포료AD적진단표준。수착대AD인식적심입급신진치기술적발전，AD적진단표준야발생료교대개변，여경가중시대경도인지공능장애계단적식별，이급재진단표준중납입생물표지물등，단불동표준지간야존재착교대적차이。인차，본문취AD진단표준적연변주일종술。
Alzheimer disease( AD) is the most common cause of dementia,and it has caused a huge economic burden to our country and other nations.Therefore, how to carry out an effective prevention and treatment strategy in the early stage of the disease,has become the key of the treatment of AD.In 1984,the National Institute of Neurological and Communicative Disorders and Stroke,and the Alzheimer Disease and Related Disorders Association ( NINCDS-ADRDA) firstly announced.With the development of our understanding of AD as well as the new technologies coming out,the diagnostic criteria also develope significantly,such as the more emphasis on mild cognitive impairment( MCI) stage and putting the biomarkers into the diagnostic criteria.However,there are significant differences among diverse standards (e.g.IGW,NIA-AA,etc),so we summized this article reviewed the changes of the AD diagnostic criteria,and gave a detail discussion about them.