国际输血及血液学杂志
國際輸血及血液學雜誌
국제수혈급혈액학잡지
INTERNATIONAL JOURNAL OF BLOOD TRANSFUSION AND HEMATOLOGY
2015年
3期
262-265
,共4页
紫癜,血小板减少性,特发性%抗原呈递细胞%T淋巴细胞%B淋巴细胞%发病机制
紫癜,血小闆減少性,特髮性%抗原呈遞細胞%T淋巴細胞%B淋巴細胞%髮病機製
자전,혈소판감소성,특발성%항원정체세포%T림파세포%B림파세포%발병궤제
Purpura,thrombocytopenic,idiopathic%Antigen presenting cell%T-lymphocytes%B-lymphocytes%Pathogenesis
特发性血小板减少性紫癜(ITP)是一种自身免疫性疾病,发病机制尚未完全明确.目前研究证实,ITP患者体内存在抗原呈递细胞(APC)与T及B淋巴细胞异常.笔者拟就APC与T及B淋巴细胞异常,以及3者间相互作用在ITP发病机制中的作用进行综述,为进一步了解ITP发病机制提供参考.
特髮性血小闆減少性紫癜(ITP)是一種自身免疫性疾病,髮病機製尚未完全明確.目前研究證實,ITP患者體內存在抗原呈遞細胞(APC)與T及B淋巴細胞異常.筆者擬就APC與T及B淋巴細胞異常,以及3者間相互作用在ITP髮病機製中的作用進行綜述,為進一步瞭解ITP髮病機製提供參攷.
특발성혈소판감소성자전(ITP)시일충자신면역성질병,발병궤제상미완전명학.목전연구증실,ITP환자체내존재항원정체세포(APC)여T급B림파세포이상.필자의취APC여T급B림파세포이상,이급3자간상호작용재ITP발병궤제중적작용진행종술,위진일보료해ITP발병궤제제공삼고.
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease,and its pathogenesis is not entirely clear so far.At present,it has been proved that the abnormalities of antigenpresenting cell (APC),T and B lymphocyte existed in ITP patients.In this paper,the role of APC,T and B lymphocyte abnormalities and the interactions among these three kinds of cells will be reviewed in order to provide a reference for further understanding of the pathogenesis of ITP.
