CAJ | 학술논문

小分子靶向抗肿瘤药物是当前国内外创新药研发的热点，近些年来不断有新产品上市，还有数百个产品正处于临床研发阶段。本文介绍了目前比较新颖和热门的抗肿瘤靶点，并列举了这些靶点比较有价值的代表性药物。随着生命科学和药学的发展，今后必将发现更多、更有效的靶点和药效更好、毒性更小的化合物，为肿瘤治疗提供新途径。
소분자파향항종류약물시당전국내외창신약연발적열점，근사년래불단유신산품상시，환유수백개산품정처우림상연발계단。본문개소료목전비교신영화열문적항종류파점，병열거료저사파점비교유개치적대표성약물。수착생명과학화약학적발전，금후필장발현경다、경유효적파점화약효경호、독성경소적화합물，위종류치료제공신도경。
At present, the molecular targeted small-molecule anti-tumor drug becomes a hot topic of domestic and for-eign research and development of innovative drugs. There are always new products having been launched, and hundreds of products are in the clinical development stage in recent years. In this paper, we introduced some hot anti-tumor targets, and listed the representative drugs of these targets. With the development of bioscience and pharmacy, more and more effective targets will be found, and more effective but less toxic compounds will be produced to provide a new approach for the treat-ment of tumor in the future.