中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2015年
7期
597-600
,共4页
凌莉%李小强%张素平%尹义臣%王慕真%何锐%邓婉青
凌莉%李小彊%張素平%尹義臣%王慕真%何銳%鄧婉青
릉리%리소강%장소평%윤의신%왕모진%하예%산완청
急性脑梗死%老年人%中青年%危险因素
急性腦梗死%老年人%中青年%危險因素
급성뇌경사%노년인%중청년%위험인소
Acute cerebral infarction%Elderly%Middle aged%Risk factors
目的 探讨老老年(≥80岁)急性脑梗死的危险因素、严重程度和梗死部位的特征.方法 选取2012年1月至2015年3月在我院住院的急性脑梗死患者162例,根据年龄分为≥80岁老年组88例和中青年(＜60岁)组74例.对其危险因素、入院时的美国国立卫生研究院脑卒中量表(NIHSS)评分和牛津郡社区脑卒中项目(OCSP)分型进行比较分析.结果 ≥80岁老年组患者伴冠心病(25.0％,22/88)、心房颤动(13.6％,12/88)高于中青年组[12.2％(9/47)与4.1％(3/74)],两组比较差异均有统计学意义(x2值分别为4.281、4.393,P均＜0.05);≥80岁老年组患者入院时NIHSS评分[(7.740±4.986)分]高于中青年组[(5.040±4.305)分],两组比较差异有统计学意义(t=-3.649,P＜0.001).Logistic回归分析发现:吸烟、高血脂、入院NIHSS评分高和性别(男)是急性脑梗死的独立危险因素(OR值分别为3.851、3.609、1.100、2.670,P均＜0.05);≥80岁老年组中腔隙性梗死分型比率(40.9％,36/88)低于中青年组(60.8％,45/74),两组比较差异有统计学意义(x2=6.369,P＜0.05).结论 与中青年相比,≥80岁老年人发生急性脑梗死时病情更加严重,其危险因素和脑梗死部位等方面有其特殊性.应及时干预≥80岁老年患者脑梗死的危险因素,正确采取有效的防治措施,提高对≥80岁老年脑梗死的治疗效果.
目的 探討老老年(≥80歲)急性腦梗死的危險因素、嚴重程度和梗死部位的特徵.方法 選取2012年1月至2015年3月在我院住院的急性腦梗死患者162例,根據年齡分為≥80歲老年組88例和中青年(＜60歲)組74例.對其危險因素、入院時的美國國立衛生研究院腦卒中量錶(NIHSS)評分和牛津郡社區腦卒中項目(OCSP)分型進行比較分析.結果 ≥80歲老年組患者伴冠心病(25.0％,22/88)、心房顫動(13.6％,12/88)高于中青年組[12.2％(9/47)與4.1％(3/74)],兩組比較差異均有統計學意義(x2值分彆為4.281、4.393,P均＜0.05);≥80歲老年組患者入院時NIHSS評分[(7.740±4.986)分]高于中青年組[(5.040±4.305)分],兩組比較差異有統計學意義(t=-3.649,P＜0.001).Logistic迴歸分析髮現:吸煙、高血脂、入院NIHSS評分高和性彆(男)是急性腦梗死的獨立危險因素(OR值分彆為3.851、3.609、1.100、2.670,P均＜0.05);≥80歲老年組中腔隙性梗死分型比率(40.9％,36/88)低于中青年組(60.8％,45/74),兩組比較差異有統計學意義(x2=6.369,P＜0.05).結論 與中青年相比,≥80歲老年人髮生急性腦梗死時病情更加嚴重,其危險因素和腦梗死部位等方麵有其特殊性.應及時榦預≥80歲老年患者腦梗死的危險因素,正確採取有效的防治措施,提高對≥80歲老年腦梗死的治療效果.
목적 탐토로노년(≥80세)급성뇌경사적위험인소、엄중정도화경사부위적특정.방법 선취2012년1월지2015년3월재아원주원적급성뇌경사환자162례,근거년령분위≥80세노년조88례화중청년(＜60세)조74례.대기위험인소、입원시적미국국립위생연구원뇌졸중량표(NIHSS)평분화우진군사구뇌졸중항목(OCSP)분형진행비교분석.결과 ≥80세노년조환자반관심병(25.0％,22/88)、심방전동(13.6％,12/88)고우중청년조[12.2％(9/47)여4.1％(3/74)],량조비교차이균유통계학의의(x2치분별위4.281、4.393,P균＜0.05);≥80세노년조환자입원시NIHSS평분[(7.740±4.986)분]고우중청년조[(5.040±4.305)분],량조비교차이유통계학의의(t=-3.649,P＜0.001).Logistic회귀분석발현:흡연、고혈지、입원NIHSS평분고화성별(남)시급성뇌경사적독립위험인소(OR치분별위3.851、3.609、1.100、2.670,P균＜0.05);≥80세노년조중강극성경사분형비솔(40.9％,36/88)저우중청년조(60.8％,45/74),량조비교차이유통계학의의(x2=6.369,P＜0.05).결론 여중청년상비,≥80세노년인발생급성뇌경사시병정경가엄중,기위험인소화뇌경사부위등방면유기특수성.응급시간예≥80세노년환자뇌경사적위험인소,정학채취유효적방치조시,제고대≥80세노년뇌경사적치료효과.
Objective To investigate the risk factors,severity and infarct site features and clinical characteristics of the elderly patients over 80 years with cute cerebral infarction.Methods One hundred and sixty-two patients with acute cerebral infarction in Red Cross Hospital of Guangzhou,The Forth Affiliated Hospital of Medical College of Jinan University from January 2012 to May 2015 were enrolled and randomly divided into the elderly patients (≥ 80 years old) and the middle aged patients (＜ 60 years old).The risk factors,national institutes of health stroke scale (NIHSS) scores and Oxfordshire community stroke project (OCSP) criteria were compared between the two groups.Results Coronary artery disease,atrial fibrillation and NIHSS in the elderly patients (25％ (22/88),13.6％ (12/88),7.74 ± 4.986) were significantly higher than those of the middle aged group (12.2％ (9/47),4.1％ (3/74),5.04± 4.305),and the differences were significant (x2 =4.281,4.393,t =-3.649;P＜ 0.05 or P＜ 0.001).The logistic regression analysis finally showed that smoking,hyperlipemia,NIHSS scores and gender(male) were the independent risk factors(OR=3.851,3.609,1.100 and 2.670;P＜0.05).There were more LACI patients in the elderly group than he middle aged group ((40.9％,36/88) vs.(60.8％,45/74),x2 =6.369,P ＜ 0.05).Conclusion Compare to the middle aged patients,occurrence of the elderly patients with acute cerebral infarction is more severe,and the clinical features and risk factors have its particularity.Secondary prevention strategy should be emphasized on the control of different risk factors based on the patients' age.
