CAJ | 학술논문

目的：研究新疆地区维吾尔族、汉族多囊卵巢综合征(PCOS)患者内分泌代谢紊乱的特点，为临床治疗提供理论依据。方法回顾性分析2014年4月~2015年5月就诊于新疆维吾尔自治区人民医院的43例维吾尔族、73例汉族PCOS患者的临床资料，对照分析维吾尔族、汉族PCOS患者的性激素水平、血糖代谢、胰岛素代谢及胰岛素抵抗等指标。结果汉族PCOS患者的糖耐量异常(AGT)患病率为27.4%(20/73)，维吾尔族PCOS的AGT患病率为2.33%(1/43)，差异有统计学意义(P<0.05)。维吾尔族PCOS患者的睾酮(T)水平较汉族高，差异有统计学意义(P<0.05)。维吾尔族OGTT和胰岛素1、2 h的水平均低于汉族，差异有统计学意义(P<0.05)。结论血脂代谢异常可能是汉族PCOS患者并发症，高T水平可能是维尔族PCOS患者的主要特征。
목적：연구신강지구유오이족、한족다낭란소종합정(PCOS)환자내분비대사문란적특점，위림상치료제공이론의거。방법회고성분석2014년4월~2015년5월취진우신강유오이자치구인민의원적43례유오이족、73례한족PCOS환자적림상자료，대조분석유오이족、한족PCOS환자적성격소수평、혈당대사、이도소대사급이도소저항등지표。결과한족PCOS환자적당내량이상(AGT)환병솔위27.4%(20/73)，유오이족PCOS적AGT환병솔위2.33%(1/43)，차이유통계학의의(P<0.05)。유오이족PCOS환자적고동(T)수평교한족고，차이유통계학의의(P<0.05)。유오이족OGTT화이도소1、2 h적수평균저우한족，차이유통계학의의(P<0.05)。결론혈지대사이상가능시한족PCOS환자병발증，고T수평가능시유이족PCOS환자적주요특정。
Objective To investigate the characteristics of endocrine metabolic abnormalities of Uyghur and Han pa-tients with polycystic ovary syndrome (PCOS) in Sinkiang,and to provide theroetical basis for clinilal therapy. Methods From Apirl 2014 to May 2015,clinical data of patients (43 cases was Uyghur and 73 cases was Han) with PCOS were selected from people’s hospital of Uygur Autonomous Region in Sinkiang.The indexs of sex hormone level,glucose metabolism,insulin metabolism and insulin resistance was compared between Uyghur and Han PCOS patients respec-tively. Results The morbidity of AGT (Abnormal glucose tolerance, AGT) in the Han PCOS patients was 27.40%(20/73),while the Uyghur was 2.33%(1/43),with statistical difference(P<0.05).Compared with the Han PCOS patients,the an-drogen level in Uyghur PCOS patients was higher,with statistical difference (P<0.05).Levels of OGTT and insulin in 1 h and 2 h of the Uyghur was lower than that of the Han respectively,with statistical difference (P<0.05). Conclusion The blood lipid metabolic abnormalities may be the complications of Han PCOS patients and high androgen level may be the main feature of Uyghur PCOS patients.