CAJ | 학술논문

间充质干细胞（MSC）内在的肿瘤趋向性和固有的低免疫原性，使其可能成为肿瘤靶向治疗的理想载体。MSC 本身可通过释放细胞因子发挥一定的抗肿瘤作用，而通过溶瘤病毒、抗血管生成药物、肿瘤坏死因子诱导凋亡配体、IL、IFN 及前体药物修饰的 MSC 抗肿瘤效果进一步加强。另外，MSC 联合其他治疗也显示出一定的优势。
간충질간세포（MSC）내재적종류추향성화고유적저면역원성，사기가능성위종류파향치료적이상재체。MSC 본신가통과석방세포인자발휘일정적항종류작용，이통과용류병독、항혈관생성약물、종류배사인자유도조망배체、IL、IFN 급전체약물수식적 MSC 항종류효과진일보가강。령외，MSC 연합기타치료야현시출일정적우세。
Mesenchymal stem cells (MSCs)have inherent tumor-trophic migratory properties and low immunogenicity,which allow them to serve as vehicles for delivering effective,targeted therapy to tumors.MSC plays an anti-tumor role by releasing some cytokines,which can be strengthened by oncolytic virus,antiangio-genesis agent,tumor necrosis factor guided apoptosis ligand,IL,IFN and pro-drug.In addition,there are some advantages in combination treatment of MSC and others therapies.