CAJ | 학술논문

目的：分析1990和2010年中国人群感染性疾病的疾病负担。方法利用2010年全球疾病负担研究结果，主要指标包括发病数和发病率，死亡数和死亡率，过早死亡损失寿命年(YLL)、伤残损失寿命年(YLD)和伤残调整寿命年(DALY)。以2010年全国人口普查数据作为标准人口，计算标化的发病率、死亡率、DALY率、YLL率和YLD率，分性别和年龄对中国1990和2010年感染性疾病发病及死亡水平和疾病负担情况进行对比分析。结果中国1990年感染性疾病的发病数、标化发病率分别为306746.92万例、242669.34/10万，死亡数、标化死亡率分别为82.43万例、72.27/10万，DALY、标化DALY率分别为5893.77万人年、3992.85年/10万，YLL、标化YLL率分别为4650.41万人年、2932.99年/10万，YLD和标化YLD率分别为1243.36万人年和1059.86年/10万；2010年相应指标均有所降低，发病数、标化发病率分别为306598.58万例、224351.66/10万，死亡数、标化死亡率分别为38.86万例、30.74/10万，DALY、标化DALY率分别为1949.22万人年、1440.75年/10万，YLL、标化YLL率分别为1204.57万人年、891.87年/10万，YLD和标化YLD率分别为744.65万人年和548.89年/10万。2010年与1990年相比，50～69岁人群发病数、发病率、死亡数、死亡率、DALY、DALY率、YLL、YLL率、YLD和YLD率增幅分别为56.84%、-9.85%、-33.07%、-61.54%、-27.68%、-58.42%、-32.46%、-61.17%、-16.75%和-52.13%；≥70岁人群增幅分别为57.90%、-5.86%、7.41%、-36.12%、-5.00%、-43.51%、-5.14%、-43.59%、-4.52%和-43.2%。结论与1990年相比，2010年中国人群感染性疾病负担下降，≥50岁人群感染性疾病发病数有所增加。
목적：분석1990화2010년중국인군감염성질병적질병부담。방법이용2010년전구질병부담연구결과，주요지표포괄발병수화발병솔，사망수화사망솔，과조사망손실수명년(YLL)、상잔손실수명년(YLD)화상잔조정수명년(DALY)。이2010년전국인구보사수거작위표준인구，계산표화적발병솔、사망솔、DALY솔、YLL솔화YLD솔，분성별화년령대중국1990화2010년감염성질병발병급사망수평화질병부담정황진행대비분석。결과중국1990년감염성질병적발병수、표화발병솔분별위306746.92만례、242669.34/10만，사망수、표화사망솔분별위82.43만례、72.27/10만，DALY、표화DALY솔분별위5893.77만인년、3992.85년/10만，YLL、표화YLL솔분별위4650.41만인년、2932.99년/10만，YLD화표화YLD솔분별위1243.36만인년화1059.86년/10만；2010년상응지표균유소강저，발병수、표화발병솔분별위306598.58만례、224351.66/10만，사망수、표화사망솔분별위38.86만례、30.74/10만，DALY、표화DALY솔분별위1949.22만인년、1440.75년/10만，YLL、표화YLL솔분별위1204.57만인년、891.87년/10만，YLD화표화YLD솔분별위744.65만인년화548.89년/10만。2010년여1990년상비，50～69세인군발병수、발병솔、사망수、사망솔、DALY、DALY솔、YLL、YLL솔、YLD화YLD솔증폭분별위56.84%、-9.85%、-33.07%、-61.54%、-27.68%、-58.42%、-32.46%、-61.17%、-16.75%화-52.13%；≥70세인군증폭분별위57.90%、-5.86%、7.41%、-36.12%、-5.00%、-43.51%、-5.14%、-43.59%、-4.52%화-43.2%。결론여1990년상비，2010년중국인군감염성질병부담하강，≥50세인군감염성질병발병수유소증가。
Objective To investigate the burden of infectious disease of the Chinese population in 1990 and 2010 and changing pattern in the past 20 years. Methods Results of the Global Burden of Disease Study 2010 (GBD 2010) were used to demonstrate the burden of infectious disease of the Chinese population in 1990 and 2010 and changing pattern from 1990 to 2010 by gender and age groups, including indicators of incidence, mortality, years of life lost due to premature mortality (YLL), years lived with disability (YLD), disability?adjusted life years (DALY), and their age?standardized rates using data of the 2010 National Census as a standard population. Results In 1990 incidence, standardized incidence rate, mortality, standardized mortality rate, DALY, standardized DALY rate, YLL, standardized YLL rate, YLD, and standardized YLD rate of infectious disease in China were 3 067 469 200 cases, 242 669.34 cases/100 000, 824 300 cases, 72.27 cases/100 000, 58 937 700 person?years(PYRS), 3 992.85 PYRS/100 000, 46 504 100 PYRS, 2 932.99 PYRS/100 000, 12 433 600 PYRS, and 1 059.86 PYRS/100 000, respectively. All the aboved indicators were declined from 1990 to 2010, in 2010 they were 3 065 985 800 cases, 224 351.66 cases/100 000, 388 600 cases, 30.74 cases/100 000, 19 492 200 PYRS, 1 440.75 PYRS/100 000, 12 045 700 PYRS, 891.87 PYRS/100 000, 7 446 500 PYRS, and 548.89 PYRS/100 000, respectively. When 2010's indicators were compared to those in 1990, the rates of increase of incidence, incidence rate, mortality, mortality rate, DALY, DALY rate, YLL, YLL rate, YLD, and YLD rate were 56.84%,-9.85%,-33.07%,-61.54%,-27.68%,-58.42%,-32.46%,-61.17%,-16.75%, and-52.13%for 50-69 age group;for≥70 age group,57.90%,-5.86%, 7.41%, -36.12%, -5.00%, -43.51%, -5.14%,-43.59%, -4.52%, and-43.2%. Conclusions The burden of infectious disease of the Chinese population was declined from 1990 to 2010;however, the incidence of infectious disease was increased in≥50 age groups.