中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
20期
26-28
,共3页
急性胰腺炎%营养治疗%双歧杆菌四联活菌片
急性胰腺炎%營養治療%雙歧桿菌四聯活菌片
급성이선염%영양치료%쌍기간균사련활균편
Acute pancreatitis%Nutritional therapy%Bifidobacterium tetravaccine tablet (live)
目的：探讨双歧杆菌四联活菌片在急性胰腺炎患者肠内营养治疗中的应用效果。方法选取2011年7月~2014年7月本院收治的98例急性胰腺炎患者作为研究对象，随机分成观察组和对照组，各49例。两组均采用急性胰腺炎常规治疗措施，对照组在常规治疗的基础上给予肠内营养治疗，观察组在对照组的基础上在营养液中加入双歧杆菌四联活菌片治疗，比较两组治疗后的C反应蛋白(CRP)、白介素-6(IL-6)、肿瘤坏死因子(TNF-α)、外周血中内毒素(ET)水平，并记录两组的症状缓解时间、体征缓解时间、首次排气与排便时间、住院时间及不良反应发生率等。结果观察组治疗后的CRP、IL-6、TNF-α、ET水平显著低于对照组，差异有统计学意义(P<0.05)。观察组的症状缓解时间、体征缓解时间、首次排气与排便时间、住院时间显著短于对照组，差异有统计学意义(P<0.05)。观察组的不良反应发生率显著低于对照组，差异有统计学意义(P<0.05)。结论在急性胰腺炎的营养治疗中加用双歧杆菌四联活菌片，不仅能够在一定程度上提高临床疗效，且可以降低常规治疗产生的不良反应发生率，值得临床推广应用。
目的：探討雙歧桿菌四聯活菌片在急性胰腺炎患者腸內營養治療中的應用效果。方法選取2011年7月~2014年7月本院收治的98例急性胰腺炎患者作為研究對象，隨機分成觀察組和對照組，各49例。兩組均採用急性胰腺炎常規治療措施，對照組在常規治療的基礎上給予腸內營養治療，觀察組在對照組的基礎上在營養液中加入雙歧桿菌四聯活菌片治療，比較兩組治療後的C反應蛋白(CRP)、白介素-6(IL-6)、腫瘤壞死因子(TNF-α)、外週血中內毒素(ET)水平，併記錄兩組的癥狀緩解時間、體徵緩解時間、首次排氣與排便時間、住院時間及不良反應髮生率等。結果觀察組治療後的CRP、IL-6、TNF-α、ET水平顯著低于對照組，差異有統計學意義(P<0.05)。觀察組的癥狀緩解時間、體徵緩解時間、首次排氣與排便時間、住院時間顯著短于對照組，差異有統計學意義(P<0.05)。觀察組的不良反應髮生率顯著低于對照組，差異有統計學意義(P<0.05)。結論在急性胰腺炎的營養治療中加用雙歧桿菌四聯活菌片，不僅能夠在一定程度上提高臨床療效，且可以降低常規治療產生的不良反應髮生率，值得臨床推廣應用。
목적：탐토쌍기간균사련활균편재급성이선염환자장내영양치료중적응용효과。방법선취2011년7월~2014년7월본원수치적98례급성이선염환자작위연구대상，수궤분성관찰조화대조조，각49례。량조균채용급성이선염상규치료조시，대조조재상규치료적기출상급여장내영양치료，관찰조재대조조적기출상재영양액중가입쌍기간균사련활균편치료，비교량조치료후적C반응단백(CRP)、백개소-6(IL-6)、종류배사인자(TNF-α)、외주혈중내독소(ET)수평，병기록량조적증상완해시간、체정완해시간、수차배기여배편시간、주원시간급불량반응발생솔등。결과관찰조치료후적CRP、IL-6、TNF-α、ET수평현저저우대조조，차이유통계학의의(P<0.05)。관찰조적증상완해시간、체정완해시간、수차배기여배편시간、주원시간현저단우대조조，차이유통계학의의(P<0.05)。관찰조적불량반응발생솔현저저우대조조，차이유통계학의의(P<0.05)。결론재급성이선염적영양치료중가용쌍기간균사련활균편，불부능구재일정정도상제고림상료효，차가이강저상규치료산생적불량반응발생솔，치득림상추엄응용。
Objective To explore the application effect of Bifidobacterium tetravaccine tablets (live) in enteral nutrition therapy in patients with acute pancreatitis. Methods 98 patients with acute pancreatitis from July 2011 to July 2014 in our hospital were selected and randomly divided into the observation group and the control group,49 cases in each group.The conventional therapeutic measures for acute pancreatitis was given in two groups.The control group was treated with enteral nutrition on the basis of conventional treatment,the observation group was treated with Bifidobac-te rium tetravaccine tablets (live) on the basis of the control group.The level of C-reactive protein (CRP),interleukin-6 (IL-6),tumor necrosis factor-α (TNF-α) and peripheral blood endotoxin (ET) after treatment in two groups was com-pared,as well as the time of symptoms and signs,the first time of exhaust and defecation,the length of hospital stay,the incidence of adverse reaction in two groups was recorded. Results The level of CRP,IL-6,TNF-α and ET in the obser-vation group after treatment was lower than that in the control group,with significant difference (P<0.05).The time of symptoms and signs,the first time of exhaust and defecation,the length of hospital stay in the observation group was shorter than that in the control group,with significant difference(P<0.05).The incidence of adverse reaction in the obser-vation group was lowter than that in the control group,with significant difference (P<0.05). Conclusion Bifidobacterium tetravaccine tablets (live) being added in the nutritional therapy of acute pancreatitis,not only can improve the clinical efficacy from a certain extent,but also can reduce the incidence of adverse reaction due to conventional therapy,it is worthy of clinical promotion and application.
