中华消化杂志
中華消化雜誌
중화소화잡지
Chinese Journal of Digestion
2015年
7期
460-464
,共5页
罗昶%吕尚泽%白涛%向雪莲%侯晓华
囉昶%呂尚澤%白濤%嚮雪蓮%侯曉華
라창%려상택%백도%향설련%후효화
功能性便秘%便秘型肠易激综合征%生活因素%逻辑回归%决策树
功能性便祕%便祕型腸易激綜閤徵%生活因素%邏輯迴歸%決策樹
공능성편비%편비형장역격종합정%생활인소%라집회귀%결책수
Functional constipation%Constipation-predominant irritable bowel syndrome%Lifestyle factors%Logistic regression%Decision trees
目的比较功能性便秘（FC）与便秘型 IBS 患者相关生活因素的差异。方法纳入2011年2月至2014年12月的255例慢性便秘患者，其中 FC 170例，便秘型 IBS 85例。另纳入同期1年内无消化道症状的170名健康者作为对照组。收集所有纳入者的人口学基本资料、生活习惯资料等。先行单因素分析，将差异有统计学意义的变量纳入多因素 Logistic 回归分析。再将 FC 和便秘型 IBS 的各因素纳入决策树模型，分析不同分类下影响因素的作用。结果单因素分析显示，FC 组与便秘型 IBS 组各生活因素比较差异均无统计学意义（P 均＞0．05）。多因素 Logistic 回归分析显示，与 FC 组比较，便秘型 IBS 组未发现独立保护或危险因素。经过决策树模型分析，最终纳入 BMI、每日饮水量和便秘家族史3个变量，当 BMI＜23．56 kg／m2（除外18．74～＜19．83 kg／m2）时，患 FC 的概率高（最高达79．75％）；当BMI 为18．74～＜19．83 kg／m2，每日饮水量少（＜1 L）时，患 FC 的概率高（66．67％）；当 BMI≥23．56 kg／m2，有便秘家族史时，患便秘型 IBS 的概率最高（70．00％）。该模型的整体预测准确率为64．6％（42／65）， AUC 值为0．688。结论FC 和便秘型 IBS 的发生与多种生活因素密切相关，BMI 低和每日饮水量少是FC 的影响因素，BMI 较高和有便秘家族史是便秘型 IBS 的影响因素。
目的比較功能性便祕（FC）與便祕型 IBS 患者相關生活因素的差異。方法納入2011年2月至2014年12月的255例慢性便祕患者，其中 FC 170例，便祕型 IBS 85例。另納入同期1年內無消化道癥狀的170名健康者作為對照組。收集所有納入者的人口學基本資料、生活習慣資料等。先行單因素分析，將差異有統計學意義的變量納入多因素 Logistic 迴歸分析。再將 FC 和便祕型 IBS 的各因素納入決策樹模型，分析不同分類下影響因素的作用。結果單因素分析顯示，FC 組與便祕型 IBS 組各生活因素比較差異均無統計學意義（P 均＞0．05）。多因素 Logistic 迴歸分析顯示，與 FC 組比較，便祕型 IBS 組未髮現獨立保護或危險因素。經過決策樹模型分析，最終納入 BMI、每日飲水量和便祕傢族史3箇變量，噹 BMI＜23．56 kg／m2（除外18．74～＜19．83 kg／m2）時，患 FC 的概率高（最高達79．75％）；噹BMI 為18．74～＜19．83 kg／m2，每日飲水量少（＜1 L）時，患 FC 的概率高（66．67％）；噹 BMI≥23．56 kg／m2，有便祕傢族史時，患便祕型 IBS 的概率最高（70．00％）。該模型的整體預測準確率為64．6％（42／65）， AUC 值為0．688。結論FC 和便祕型 IBS 的髮生與多種生活因素密切相關，BMI 低和每日飲水量少是FC 的影響因素，BMI 較高和有便祕傢族史是便祕型 IBS 的影響因素。
목적비교공능성편비（FC）여편비형 IBS 환자상관생활인소적차이。방법납입2011년2월지2014년12월적255례만성편비환자，기중 FC 170례，편비형 IBS 85례。령납입동기1년내무소화도증상적170명건강자작위대조조。수집소유납입자적인구학기본자료、생활습관자료등。선행단인소분석，장차이유통계학의의적변량납입다인소 Logistic 회귀분석。재장 FC 화편비형 IBS 적각인소납입결책수모형，분석불동분류하영향인소적작용。결과단인소분석현시，FC 조여편비형 IBS 조각생활인소비교차이균무통계학의의（P 균＞0．05）。다인소 Logistic 회귀분석현시，여 FC 조비교，편비형 IBS 조미발현독립보호혹위험인소。경과결책수모형분석，최종납입 BMI、매일음수량화편비가족사3개변량，당 BMI＜23．56 kg／m2（제외18．74～＜19．83 kg／m2）시，환 FC 적개솔고（최고체79．75％）；당BMI 위18．74～＜19．83 kg／m2，매일음수량소（＜1 L）시，환 FC 적개솔고（66．67％）；당 BMI≥23．56 kg／m2，유편비가족사시，환편비형 IBS 적개솔최고（70．00％）。해모형적정체예측준학솔위64．6％（42／65）， AUC 치위0．688。결론FC 화편비형 IBS 적발생여다충생활인소밀절상관，BMI 저화매일음수량소시FC 적영향인소，BMI 교고화유편비가족사시편비형 IBS 적영향인소。
Objective To compare the differences of lifestyle factors between patients with functional constipation (FC)and constipation-predominant irritable bowel syndrome (IBS-C).Methods From February 2011 to December 2014,255 patients with chronic constipation were enrolled.Among them,there were 170 FC patients and 85 IBS-C patients.At the same period,170 healthy volunteers without symptoms of digestive diseases within one year were recruited as control.The data of demographic information and lifestyle factors were collected.First,single variant analysis was performed for statistical analysis and then the statistically significant variants were analyzed by multivariate logistic regression. Then the factors of FC and IBS-C patients were analyzed by decision tree model and the effects of factors under different categories were analyzed.Results The results of single variant analysis indicated that there was no difference in lifestyle factors between FC group and IBS-C group (all P >0.05).The results of multivariate logistic regression analysis showed that no independent protective or risk factors were found in IBS-C group compared with FC group.According to decision tree model analysis,body mass index (BMI),water intake per day and constipation family history were finally enrolled.The incidence of FC was higher in patients with BMI < 23.56 kg/m2 (except 18.74 to < 19.83 kg/m2 )(79.75 %).The incidence of FC was higher in patients with BMI from 18.74 to <19.83 kg/m2 and water intake <1 L <br> (66.67%).The incidence of FC was highest in patients with BMI≥23.56 kg/m2 and family history of constipation (70.00%).The total prediction accuracy of this model was 64.6% (42/65 )and area under curve (AUC)value was 0.688.Conclusions FC and IBS-C are related with many lifestyle factors.Low BMI and less water intake per day are influence factors of FC,while higher BMI and family history of constipation are influence factors of IBS-C.
