CAJ | 학술논문

目的：观察参芪五子降脂汤治疗高血脂症的临床效果。方法选取2012年1月至2014年4月间收治的120例高血脂症患者为研究对象，将其按照随机数字法分为对照组和治疗组，对照组常规给予辛伐他汀治疗，治疗组给予中药参芪五子降脂汤加减治疗，8周为一个疗程，一个疗程后观察两组患者的临床疗效及不良反应。结果治疗组总有效率为91.67%，对照组总有效率为78.33%，治疗组的临床疗效明显优于对照组（ P ﹤0.05）。两组治疗后各项血脂指标均显著改善，且治疗组优于对照组（ P ﹤0.05）。两组不良反应发生率无统计学差异（ P ﹤0.05）。结论中药参芪五子降脂汤加减治疗高血脂症效果显著，且无明显不良反应，值得临床推广应用。
목적：관찰삼기오자강지탕치료고혈지증적림상효과。방법선취2012년1월지2014년4월간수치적120례고혈지증환자위연구대상，장기안조수궤수자법분위대조조화치료조，대조조상규급여신벌타정치료，치료조급여중약삼기오자강지탕가감치료，8주위일개료정，일개료정후관찰량조환자적림상료효급불량반응。결과치료조총유효솔위91.67%，대조조총유효솔위78.33%，치료조적림상료효명현우우대조조（ P ﹤0.05）。량조치료후각항혈지지표균현저개선，차치료조우우대조조（ P ﹤0.05）。량조불량반응발생솔무통계학차이（ P ﹤0.05）。결론중약삼기오자강지탕가감치료고혈지증효과현저，차무명현불량반응，치득림상추엄응용。
Objective To investigate the clinical effect of shenqiwuzijiangzhi decoction on hyperlipaemia. Methods One hundred twenty cases of hyperlipaemia were randomly divided into treatment group and control group,the patients in the control group were treated with simvasta-tin,the patients in treatment group were treated with shenqiwuzijiangzhi decoction. The clinical effect and side effect were evaluated after 8 weeks of treatment in both groups. Results The total effective rate in the treatment group(91. 67% )was higher than the control group(78. 33% )( P ﹤ 0. 05). The lipid parameters in both groups were improved,but the improvement was more significant in treatment group than control group( P ﹤ 0. 05). The incidence of adverse events in two group had no statistically significant difference( P ﹥ 0. 05). Conclusion Shenqiwuzijiangzhi decoction is effective and safe for the treatment of hyperlipaemia.