临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2015年
15期
1262-1264
,共3页
老年人%代谢综合征%心率变异性
老年人%代謝綜閤徵%心率變異性
노년인%대사종합정%심솔변이성
Elderly patients%Metabolic syndrome%Heart rate variability
目的：分析老年代谢综合征（MS）患者的心率变异性（HRV），探讨老年代谢综合征对心脏自主神经功能的影响及意义。方法选择在内科就诊并行动态心电图检查的55岁以上老年患者103例，测量身高、体重、血压、空腹血糖、甘油三酯（TG）、高密度脂蛋白（HDL - C），并计算体重指数（BMI）。根据中华医学会糖尿病学分会（CDS）建议代谢综合征的诊断标准分为 MS 组57例和对照组46例，同时将 MS 组分为糖尿病组39例和非糖尿病组18例两亚组，分别比较两组 HRV 时域指标（ SDNN、SDANNindex、SDNNindex、rMSSD、PNN50）。结果 MS 组与对照组比较，MS 组的HRV 时域指标值下降，差异有统计学意义（ P ﹤0.05）；MS 组中糖尿病与非糖尿病组比较，糖尿病组 HRV 时域指标值下降明显，差异有统计学意义（ P ﹤0.05）。结论老年 MS 患者，尤其伴有糖尿病者，HRV 降低，提示心脏自主神经的调节功能受损，心血管危险因素增加。应加强对老年 MS 患者 HRV 的检测，控制高血糖、高血压、高血脂等危险因素，预防心血管事件的发生。
目的：分析老年代謝綜閤徵（MS）患者的心率變異性（HRV），探討老年代謝綜閤徵對心髒自主神經功能的影響及意義。方法選擇在內科就診併行動態心電圖檢查的55歲以上老年患者103例，測量身高、體重、血壓、空腹血糖、甘油三酯（TG）、高密度脂蛋白（HDL - C），併計算體重指數（BMI）。根據中華醫學會糖尿病學分會（CDS）建議代謝綜閤徵的診斷標準分為 MS 組57例和對照組46例，同時將 MS 組分為糖尿病組39例和非糖尿病組18例兩亞組，分彆比較兩組 HRV 時域指標（ SDNN、SDANNindex、SDNNindex、rMSSD、PNN50）。結果 MS 組與對照組比較，MS 組的HRV 時域指標值下降，差異有統計學意義（ P ﹤0.05）；MS 組中糖尿病與非糖尿病組比較，糖尿病組 HRV 時域指標值下降明顯，差異有統計學意義（ P ﹤0.05）。結論老年 MS 患者，尤其伴有糖尿病者，HRV 降低，提示心髒自主神經的調節功能受損，心血管危險因素增加。應加彊對老年 MS 患者 HRV 的檢測，控製高血糖、高血壓、高血脂等危險因素，預防心血管事件的髮生。
목적：분석노년대사종합정（MS）환자적심솔변이성（HRV），탐토노년대사종합정대심장자주신경공능적영향급의의。방법선택재내과취진병행동태심전도검사적55세이상노년환자103례，측량신고、체중、혈압、공복혈당、감유삼지（TG）、고밀도지단백（HDL - C），병계산체중지수（BMI）。근거중화의학회당뇨병학분회（CDS）건의대사종합정적진단표준분위 MS 조57례화대조조46례，동시장 MS 조분위당뇨병조39례화비당뇨병조18례량아조，분별비교량조 HRV 시역지표（ SDNN、SDANNindex、SDNNindex、rMSSD、PNN50）。결과 MS 조여대조조비교，MS 조적HRV 시역지표치하강，차이유통계학의의（ P ﹤0.05）；MS 조중당뇨병여비당뇨병조비교，당뇨병조 HRV 시역지표치하강명현，차이유통계학의의（ P ﹤0.05）。결론노년 MS 환자，우기반유당뇨병자，HRV 강저，제시심장자주신경적조절공능수손，심혈관위험인소증가。응가강대노년 MS 환자 HRV 적검측，공제고혈당、고혈압、고혈지등위험인소，예방심혈관사건적발생。
Objective To explore the variation of heart rate in elderly patients with metabolic syndrome(MS),and to explore the signifi-cance of influence of elderly metabolic syndrome on cardiac autonomic nerve function. Methods A total of 103 elderly patients over 55 years old in this hospital were examined by dynamic ECG and their height,weight,blood pressure,blood levels of fasting glucose,triglyceride(TG)and high - density lipoprotein(HDL - C)were examined and their body mass index(BMI)had been calculated. They were divided into MS group(n= 57 cases)and control group(n = 46 cases)according to the diagnostic criteria of Chinese Society of Diabetes,Chinese Medical Association,at the same time patients in MS group can further be divided into diabetes subgroup(n = 39 cases)and non - diabetic subgroup(n = 18 cases),they were compared with HRV time domain indexes(SDNN,SDANN index,SDNN index,rMSSD and PNN50). Results In comparison with control group,HRV time domain indexes of MS group was declined,and their difference was statistically significant( P ﹤ 0. 05). In MS group,diabetes subgroup in comparison with non - diabetic group,HRV time domain indexes in diabetes subgroup were significantly decreased,their difference was statistically significant( P ﹤ 0. 05). Conclusion In elderly patients with MS especially associated with diabetes,the autonomic nervous function of heart has been impaired,the regulation of cardiovascular risk factors should be strengthened in the detection of HRV in old patients with MS,control of hyperglycemia,hypertension,hyperlipidemia and other risk factors are very important in order to prevent the occurrence of cardio-vascular events.
