中国卫生标准管理
中國衛生標準管理
중국위생표준관리
CHINA HEALTH STANDARD MANAGEMENT
2015年
19期
163-165
,共3页
多发性骨髓瘤%核医学影像%诊断
多髮性骨髓瘤%覈醫學影像%診斷
다발성골수류%핵의학영상%진단
Multiple myeloma%Nuclear medicine imaging%Diagnosis
目的评价核医学影像诊断多发性骨髓瘤（Multiple Myeloma，MM）的临床价值。方法以单光子发射计算机断层成像术（Single-Photon Emission Computed Tomography，SPECT）诊断62例MM患者，其中42例联合局部X线、CT、MRI检查。结果 SPECT整体敏感度90.32%；59例SPECT阳性患者，浓聚灶75.68%（140/185）；42例联合诊断患者，SPECT发现异常病灶142处，CT敏感度、特异度、阳性预测值、阴性预测值、准确率分别为94.74%、87.06%、83.08%、96.10%、90.15%，SPECT则为92.98%、83.53%、79.10%、94.67%、87.32%，均高于X线59.65%、60.00%、50.00%、68.92%、59.86%，MRI敏感度、阳性预测值高于SPECT，差异具有统计学意义（P<0.05）；阳性病灶影像学特征与病变大小有关，大面积病灶有软组织肿胀占79.55%（35/44），骨外见组织肿块、尿污染44例。结论 SPECT诊断多发性骨髓瘤效果较高，敏感度与CT/MRI相近，但检查时，需注意排除干扰因素。
目的評價覈醫學影像診斷多髮性骨髓瘤（Multiple Myeloma，MM）的臨床價值。方法以單光子髮射計算機斷層成像術（Single-Photon Emission Computed Tomography，SPECT）診斷62例MM患者，其中42例聯閤跼部X線、CT、MRI檢查。結果 SPECT整體敏感度90.32%；59例SPECT暘性患者，濃聚竈75.68%（140/185）；42例聯閤診斷患者，SPECT髮現異常病竈142處，CT敏感度、特異度、暘性預測值、陰性預測值、準確率分彆為94.74%、87.06%、83.08%、96.10%、90.15%，SPECT則為92.98%、83.53%、79.10%、94.67%、87.32%，均高于X線59.65%、60.00%、50.00%、68.92%、59.86%，MRI敏感度、暘性預測值高于SPECT，差異具有統計學意義（P<0.05）；暘性病竈影像學特徵與病變大小有關，大麵積病竈有軟組織腫脹佔79.55%（35/44），骨外見組織腫塊、尿汙染44例。結論 SPECT診斷多髮性骨髓瘤效果較高，敏感度與CT/MRI相近，但檢查時，需註意排除榦擾因素。
목적평개핵의학영상진단다발성골수류（Multiple Myeloma，MM）적림상개치。방법이단광자발사계산궤단층성상술（Single-Photon Emission Computed Tomography，SPECT）진단62례MM환자，기중42례연합국부X선、CT、MRI검사。결과 SPECT정체민감도90.32%；59례SPECT양성환자，농취조75.68%（140/185）；42례연합진단환자，SPECT발현이상병조142처，CT민감도、특이도、양성예측치、음성예측치、준학솔분별위94.74%、87.06%、83.08%、96.10%、90.15%，SPECT칙위92.98%、83.53%、79.10%、94.67%、87.32%，균고우X선59.65%、60.00%、50.00%、68.92%、59.86%，MRI민감도、양성예측치고우SPECT，차이구유통계학의의（P<0.05）；양성병조영상학특정여병변대소유관，대면적병조유연조직종창점79.55%（35/44），골외견조직종괴、뇨오염44례。결론 SPECT진단다발성골수류효과교고，민감도여CT/MRI상근，단검사시，수주의배제간우인소。
ObjectiveTo evaluate the clinical value of nuclear medicine imaging in the diagnosis of multiple myeloma (MM). Methods 62 patients with MM was diagnosed by single photon emission computed tomography, including 42 cases with local X-ray,MRI and CT examination.ResultsThe overal sensitivity of SPECT was 90.32%,59 SPECT positive patients,75.68% concentration range (140/185).42 cases of patients with combined diagnosis, SPECT found 142 lesions.CT sensitivity,specificity,positive predictive value, negative predictive value,accuracy rate were 94.74%、87.06%、83.08%、96.10%、90.15%,MRI’ were 96.49%,97.65%,96.49%,97.65%,97.18%.SPECT’ were 92.98%, 83.53%, 79.10%,94.67%,87.32%.These were higher than that of X-ray’ 59.65%、60.00%、50.00%、68.92%、59.86%.MRI sensitivity,positive predictive value were higher than SPECT,and the difference was statisticaly significant (P< 0.05).Positive lesions imaging characteristics were related to the size of the lesion,and a large area of soft tissue sweling lesions accounted for 79.55% (35/44). It could see the bone tissue mass,44 cases of urinary polution.Conclusion The utility of SPECT in the diagnosis of multiple myeloma is high, and the sensitivity is similar to CT/MRI,but it was necessary to pay attention to the exclusion of interference factors.
