微生物学免疫学进展
微生物學免疫學進展
미생물학면역학진전
PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY
2015年
5期
45-48
,共4页
张扬丽%蒋明栋%王智华%李静梅
張颺麗%蔣明棟%王智華%李靜梅
장양려%장명동%왕지화%리정매
解脲脲原体%人型支原体%混合感染%药敏试验%半定量计数
解脲脲原體%人型支原體%混閤感染%藥敏試驗%半定量計數
해뇨뇨원체%인형지원체%혼합감염%약민시험%반정량계수
Ureaplasma urealyticum%Mycoplasma hominis%Mix infection%Drug sensitivity test%Semi-quantification
目的：对门诊2709例病例的支原体培养标本进行泌尿生殖道解脲脲原体（ Ureaplasma urealyticum ，Uu）与人型支原体（ Mycoplasma hominis，Mh）感染情况及耐药性的分析，为临床的诊断及治疗提供参考依据。方法采用商品化试剂盒对2709例标本进行Uu、Mh半定量培养及药物敏感试验。结果2709例标本中总阳性率为56．15％，其中Uu占比39．87％、Mh占比8．08％、Uu和Mh共同阳性者占比8．19％，男性标本阳性率为47．78％、女性标本阳性率为66．26％。药敏结果显示，单独Uu感染者对喹诺酮类（5．00％～34．40％）、红霉素（42．80％）敏感率较低，而对四环素类（88．90％～95．00％）、交沙霉素（97．30％）敏感率较高。单独Mh感染者与Uu和Mh混合感染者耐药情况均较为严重，除四环素、强力霉素、交沙霉素、美满霉素敏感率在50％以上，对其余药物的敏感率均在50％以下。结论泌尿生殖道支原体感染以Uu感染为主，其中女性感染率高于男性；药敏结果显示感染者对四环素、强力霉素、交沙霉素、美满霉素敏感率较高，单独Mh感染者与Uu和Mh混合感染者耐药情况更为严重。
目的：對門診2709例病例的支原體培養標本進行泌尿生殖道解脲脲原體（ Ureaplasma urealyticum ，Uu）與人型支原體（ Mycoplasma hominis，Mh）感染情況及耐藥性的分析，為臨床的診斷及治療提供參攷依據。方法採用商品化試劑盒對2709例標本進行Uu、Mh半定量培養及藥物敏感試驗。結果2709例標本中總暘性率為56．15％，其中Uu佔比39．87％、Mh佔比8．08％、Uu和Mh共同暘性者佔比8．19％，男性標本暘性率為47．78％、女性標本暘性率為66．26％。藥敏結果顯示，單獨Uu感染者對喹諾酮類（5．00％～34．40％）、紅黴素（42．80％）敏感率較低，而對四環素類（88．90％～95．00％）、交沙黴素（97．30％）敏感率較高。單獨Mh感染者與Uu和Mh混閤感染者耐藥情況均較為嚴重，除四環素、彊力黴素、交沙黴素、美滿黴素敏感率在50％以上，對其餘藥物的敏感率均在50％以下。結論泌尿生殖道支原體感染以Uu感染為主，其中女性感染率高于男性；藥敏結果顯示感染者對四環素、彊力黴素、交沙黴素、美滿黴素敏感率較高，單獨Mh感染者與Uu和Mh混閤感染者耐藥情況更為嚴重。
목적：대문진2709례병례적지원체배양표본진행비뇨생식도해뇨뇨원체（ Ureaplasma urealyticum ，Uu）여인형지원체（ Mycoplasma hominis，Mh）감염정황급내약성적분석，위림상적진단급치료제공삼고의거。방법채용상품화시제합대2709례표본진행Uu、Mh반정량배양급약물민감시험。결과2709례표본중총양성솔위56．15％，기중Uu점비39．87％、Mh점비8．08％、Uu화Mh공동양성자점비8．19％，남성표본양성솔위47．78％、녀성표본양성솔위66．26％。약민결과현시，단독Uu감염자대규낙동류（5．00％～34．40％）、홍매소（42．80％）민감솔교저，이대사배소류（88．90％～95．00％）、교사매소（97．30％）민감솔교고。단독Mh감염자여Uu화Mh혼합감염자내약정황균교위엄중，제사배소、강력매소、교사매소、미만매소민감솔재50％이상，대기여약물적민감솔균재50％이하。결론비뇨생식도지원체감염이Uu감염위주，기중녀성감염솔고우남성；약민결과현시감염자대사배소、강력매소、교사매소、미만매소민감솔교고，단독Mh감염자여Uu화Mh혼합감염자내약정황경위엄중。
Objective To investigate the infection status and the drug resistance of cultured ureaplasma urealyticum ( Uu) and mycoplasma hominis( Mh) in samples collected from out-patients and to provide a basic reference evidence in diagnosis and treatment.Methods A total of 2 709 Un and Mh samples were tested with the commercial kits.Results The posi-tive rate was 56.15%, the positive rates for Uu and MH were 39.87% and 8.08% separately, and both positive for Un and Mh mixed infection was 8.19%in the total samples.The positive rate in male and femaie sample were 47.78% and 66.26%, respectively.The tested result showed that Uu patients had a low drug sensitivity to quinolones ( 5.00%-34.40%) and roxithromycin(42.80%).but a high drug sensitivity to tetracycline (88.90%-95.00%) and josamycin (97.30%)and the patients who were infected by Mh alone or co-infected by Uu and Mh had a high resistance to these drugs, the sensitivity was more than 50% for tetracycline, doxycycline, josamycin and minocycline, and was less than 50%for the other drugs.Conclusion Uu infection was predominance in the urogential infection, which was higher in fe-male than that in male.The drug sensitivity test result showed that these patients had a high sensitivity to tetracycline, dox-ycycline, josamycin and minocycline, and for the patients with Mh infection alone and the mixed infection for Uu and Mh. the drug resistance was even worse.
