中华解剖与临床杂志
中華解剖與臨床雜誌
중화해부여림상잡지
Chinese Journal of Anatomy and Clinics
2015年
4期
361-364
,共4页
软骨%骨关节炎%磁共振成像%参量值
軟骨%骨關節炎%磁共振成像%參量值
연골%골관절염%자공진성상%삼량치
Cartilage%Osteoarthritis%Magnetic resonance imaging%Parameter value
目的：探讨软骨定量 MRI 新技术在骨关节炎诊断和治疗中的研究进展和应用前景。方法在 Medline 和 CNKI 数据库,分别以“Cartilage injury/ damage, osteoarthritis, T1ρmapping, Sodium MRI, magnetization transfer MRI, Chemical exchange saturation transfer, Ultrashort echo time MRI, DWI, DTI, Pharmacokinetic MRI”和“软骨损伤,骨关节炎,T1ρ值,钠磁共振成像,磁化传递磁共振成像,化学交换依赖性饱和传递技术,扩散加权成像,扩散张量成像,药物代谢动力学磁共振成像”为关键词,限定语言种类为 English 和中文,检索2001年1月—2014年7月间发表的有关软骨损伤和软骨定量MRI 研究的文章。就检索到的200余篇文献进行筛选,选择以软骨损伤和骨关节炎 MRI 的实验研究和临床研究为主要内容的文献86篇；其中研究相似的,以近5年且发表在较权威期刊者优先纳入分析。结果软骨的 MRI 和定量分析一直是学界研究热点之一,近年来随着 MRI 硬件和软件的提升,各种 MRI 新技术被应用于软骨 MRI 的定量分析,这些新技术在检测早期软骨损伤及软骨生化成分和血管成分的量化分析方面展示了良好的应用和研究前景,但是仍存在一些固有的缺陷。结论随着MR 硬件和软件的升级、新序列的开发与运用及理论研究的不断深入,这些新技术或可成为骨关节炎诊断和治疗的 MRI 生物标志物。
目的：探討軟骨定量 MRI 新技術在骨關節炎診斷和治療中的研究進展和應用前景。方法在 Medline 和 CNKI 數據庫,分彆以“Cartilage injury/ damage, osteoarthritis, T1ρmapping, Sodium MRI, magnetization transfer MRI, Chemical exchange saturation transfer, Ultrashort echo time MRI, DWI, DTI, Pharmacokinetic MRI”和“軟骨損傷,骨關節炎,T1ρ值,鈉磁共振成像,磁化傳遞磁共振成像,化學交換依賴性飽和傳遞技術,擴散加權成像,擴散張量成像,藥物代謝動力學磁共振成像”為關鍵詞,限定語言種類為 English 和中文,檢索2001年1月—2014年7月間髮錶的有關軟骨損傷和軟骨定量MRI 研究的文章。就檢索到的200餘篇文獻進行篩選,選擇以軟骨損傷和骨關節炎 MRI 的實驗研究和臨床研究為主要內容的文獻86篇；其中研究相似的,以近5年且髮錶在較權威期刊者優先納入分析。結果軟骨的 MRI 和定量分析一直是學界研究熱點之一,近年來隨著 MRI 硬件和軟件的提升,各種 MRI 新技術被應用于軟骨 MRI 的定量分析,這些新技術在檢測早期軟骨損傷及軟骨生化成分和血管成分的量化分析方麵展示瞭良好的應用和研究前景,但是仍存在一些固有的缺陷。結論隨著MR 硬件和軟件的升級、新序列的開髮與運用及理論研究的不斷深入,這些新技術或可成為骨關節炎診斷和治療的 MRI 生物標誌物。
목적：탐토연골정량 MRI 신기술재골관절염진단화치료중적연구진전화응용전경。방법재 Medline 화 CNKI 수거고,분별이“Cartilage injury/ damage, osteoarthritis, T1ρmapping, Sodium MRI, magnetization transfer MRI, Chemical exchange saturation transfer, Ultrashort echo time MRI, DWI, DTI, Pharmacokinetic MRI”화“연골손상,골관절염,T1ρ치,납자공진성상,자화전체자공진성상,화학교환의뢰성포화전체기술,확산가권성상,확산장량성상,약물대사동역학자공진성상”위관건사,한정어언충류위 English 화중문,검색2001년1월—2014년7월간발표적유관연골손상화연골정량MRI 연구적문장。취검색도적200여편문헌진행사선,선택이연골손상화골관절염 MRI 적실험연구화림상연구위주요내용적문헌86편；기중연구상사적,이근5년차발표재교권위기간자우선납입분석。결과연골적 MRI 화정량분석일직시학계연구열점지일,근년래수착 MRI 경건화연건적제승,각충 MRI 신기술피응용우연골 MRI 적정량분석,저사신기술재검측조기연골손상급연골생화성분화혈관성분적양화분석방면전시료량호적응용화연구전경,단시잉존재일사고유적결함。결론수착MR 경건화연건적승급、신서렬적개발여운용급이론연구적불단심입,저사신기술혹가성위골관절염진단화치료적 MRI 생물표지물。
Objective To explore research progress and application prospects of new MRI technologies in diagnosis and treatment of osteoarthritis. Methods A computer-based online search of Medline database was undertaken to identify the articles about cartilage injury/ damage and cartilage quantitative MRI published in English from January 2004 to July 2014, with the key words of " Cartilage injury/ damage, osteoarthritis, T1ρmapping, Sodium MRI, magnetization transfer MRI, Chemical exchange saturation transfer, Ultrashort echo time MRI, DWI, DTI, Pharmacokinetic MRI" . And the computer-based online search of CNKI database was also undertaken to identify relevant articles published in Chinese from January 2004 to July 2014 with the key words of " 软骨损伤,骨关节炎,T1ρ 值,钠磁共振成像,磁化传递磁共振成像,化学交换±赖性?和传递技术,扩散加权成像,扩散张量成像,药物代谢动力学磁共振成像" . The first trial involved in 200 articles, and 86 articles of them referred to the experimental and clinical study of cartilage injury/ damage and osteoarthritis. In which those had similar content and published on authority magazines in recent 5 years were preferred. Results Cartilage MRI and quantitative analysis have been one of the hot-point academic researchs. In recent years, with the enhancement of MRI hardware and software, the new technology has been applied to cartilage quantitative MRI analysis. In terms of early detection of cartilage damage and cartilage biochemical composition and vascular components, quantitative analysis of these new MRI technologies showed good application and research prospects, but there were still some inherent flaws. Conclusions With MR hardware and software upgrades, the development and application of new MRI sequences and deepening of theoretical studies using these new technologies, parameter values derived these new quantitative MRI analysis techniques may become MRI biomarkers in diagnosis and treatment of osteoarthritis in the future.
