CAJ | 학술논문

目的探讨青年缺血性脑卒中(Ischemic stroke,IS)患者发病的常见相关危险因素,早期对症治疗,并降低死亡率与致残率.方法将139例青年IS患者按年龄分为两组,青年Ⅰ组46例18～34岁的青年脑梗死患者;青年Ⅱ组93例35～45岁的青年脑梗死患者;对危险因素进行回顾性分析.结果青年Ⅱ组EH、HLP、DM、吸烟、饮酒等危险因素明显高于青年Ⅰ组(P＜0.05),而青年Ⅱ组心脏疾患、血管狭窄及畸形、血管炎、高同型半胱氨酸血症的比例明显低于青年Ⅰ组(P＜0.05),两组的脑卒中史及脑卒中家族史之间比较差异无统计学意义(P＞0.05).结论青年IS的常见危险因素有EH、HLP、DM、心脏疾患、血管炎、HHE、吸烟等;其不同年龄段其病因及危险因素仍有不同的特点,脂肪代谢异常和EH是容易导致青年IS的主要原因.
목적 탐토청년결혈성뇌졸중(Ischemic stroke,IS)환자발병적상견상관위험인소,조기대증치료,병강저사망솔여치잔솔.방법 장139례청년IS환자안년령분위량조,청년Ⅰ조46례18～34세적청년뇌경사환자;청년Ⅱ조93례35～45세적청년뇌경사환자;대위험인소진행회고성분석.결과 청년Ⅱ조EH、HLP、DM、흡연、음주등위험인소명현고우청년Ⅰ조(P＜0.05),이청년Ⅱ조심장질환、혈관협착급기형、혈관염、고동형반광안산혈증적비례명현저우청년Ⅰ조(P＜0.05),량조적뇌졸중사급뇌졸중가족사지간비교차이무통계학의의(P＞0.05).결론 청년IS적상견위험인소유EH、HLP、DM、심장질환、혈관염、HHE、흡연등;기불동년령단기병인급위험인소잉유불동적특점,지방대사이상화EH시용역도치청년IS적주요원인.
Objective To investigate common risk factors of stroke ischemic (IS) in youth patients,and to reduce the mortality and disability rate.Methods 139 young patients with IS were divided into two groups according to age,46 cases in youth group Ⅰ were 18-34 years old,93 cases in youth group Ⅱ were 35-45 years old.Retrospectively analyzed risk factors.Results The rates of risk factors such as EH,HLP,DM,smoking,drinking in youth group Ⅱ were significantly higher than those in young group Ⅰ (P＜0.05),and the rates of heart disease,vascular stenosis and deformity,vasculitis,hyperhomocysteinemia in youth group Ⅱ were significantly lower than those in young group Ⅰ (P＜0.05).There were no statistically significant differences in the rates of stroke history and family history of stroke between two groups (P＞0.05).Conclusions Common risk factors of ischemic stroke in youth include EH,HLP,DM,heart disease,vasculitis,HHE,smoking.The etiology and risk factors for different age still have different characteristics.Abnormal lipid metabolism and EH are main causes of ischemic stroke in youth.