CAJ | 학술논문

碳量子点作为光功能组分和纳米载体用于构筑磁共振-荧光双模态分子探针的研究才刚刚开始。本文首次以兼作Gd3+源和碳源的钆喷酸单葡甲胺为前驱体，研究了热裂解温度、保温时间和加热速率对前驱体碳化程度、所得产物量子产率和Gd3+掺杂量的影响。结果显示，前驱体在经历合理的热裂解条件(热裂解温度不高于350℃)后，可简便地制得Gd3+螯合物掺杂的碳量子点。该碳量子点除了具有优异的发光能力外(量子产率~7.6%)，还表现出磁共振响应(纵向弛豫率~6.5 mmol-1·L·s-1)，可用作磁共振-荧光双模态分子影像探针。
탄양자점작위광공능조분화납미재체용우구축자공진-형광쌍모태분자탐침적연구재강강개시。본문수차이겸작Gd3+원화탄원적구분산단포갑알위전구체，연구료열렬해온도、보온시간화가열속솔대전구체탄화정도、소득산물양자산솔화Gd3+참잡량적영향。결과현시，전구체재경력합리적열렬해조건(열렬해온도불고우350℃)후，가간편지제득Gd3+오합물참잡적탄양자점。해탄양자점제료구유우이적발광능력외(양자산솔~7.6%)，환표현출자공진향응(종향이예솔~6.5 mmol-1·L·s-1)，가용작자공진-형광쌍모태분자영상탐침。
The study of carbon quantum dots used as either photoluminescence functional compo-nents or nano carriers for magnetic resonance-fluorescence multimodal molecular imaging probe is just beginning. In the paper, the gadopentetate monomeglumine was used as a precursor which pro-vides simultaneously carbon sources and Gd3+ sources. The influences of pyrolysis temperature, holding time and heating rate on the carbonization degree of the precursor, the quantum yield and the Gd3+ content of the products were studied. When the precursor was pyrolized under reasonable condition ( the pyrolysis temperature was not higher than 350 ℃) , Gd3+ chelates dopped carbon quantum dots were facilely prepared. The carbon quantum dots not only possessing high luminous power ( quantum yield ~7 . 6%) , but also showing good magnetic resonance response ( longitudinal relaxation rate ~6. 5 mmol-1 ·L·s-1 ) can be used as a magnetic resonance/fluorescence multi-modal molecular imaging probe.