CAJ | 학술논문

目的：探讨不同手术方式治疗甲状腺髓样癌的临床效果。方法回顾性分65例甲状腺髓样癌患者的临床资料,根据手术方式不同分为3组，A 组行甲状腺全切术+中央区颈淋巴结术，B组行保留对侧喉返神经入喉处甲状腺组织的甲状腺次全切术+双侧改良颈淋巴结清扫术， C 组行保留对侧喉返神经入喉处甲状腺组织的次全切除术+单侧改良颈淋巴结清扫术。比较生存期，治愈率，复发率及并发症发生率。结果 A、B、C三组患者生存期比较无统计学差异（P>0.05）。生化治愈率和术后复发率组间比较，差异有统计学意义（P<0.05）。A、B、C三组患者喉返神经损伤和甲状旁腺功能低下发生率比较，差异有统计学意义（P<0.05）。结论与A组比较，B、C组具有相同的术后生存期、较高的治愈率，较低的甲状旁腺功能低下和喉返神经损伤发生率以及较低的癌症复发率。
목적：탐토불동수술방식치료갑상선수양암적림상효과。방법회고성분65례갑상선수양암환자적림상자료,근거수술방식불동분위3조，A 조행갑상선전절술+중앙구경림파결술，B조행보류대측후반신경입후처갑상선조직적갑상선차전절술+쌍측개량경림파결청소술， C 조행보류대측후반신경입후처갑상선조직적차전절제술+단측개량경림파결청소술。비교생존기，치유솔，복발솔급병발증발생솔。결과 A、B、C삼조환자생존기비교무통계학차이（P>0.05）。생화치유솔화술후복발솔조간비교，차이유통계학의의（P<0.05）。A、B、C삼조환자후반신경손상화갑상방선공능저하발생솔비교，차이유통계학의의（P<0.05）。결론여A조비교，B、C조구유상동적술후생존기、교고적치유솔，교저적갑상방선공능저하화후반신경손상발생솔이급교저적암증복발솔。
ObjectiveTo explored the different surgical procedure for treatment of medulary thyroid carcinoma.Methods Retrospectively to analyze the clinical data of 65 patients with medulary thyroid carcinoma. According to different operation methods,and it was divided into 3 groups.The group A underwent total thyroidectomy and central lymph node surgery. The group B was performed with thyroid subtotal resection of thyroid tissue and bilateral lymph node dissection. The group B was performed with thyroid subtotal resection of thyroid tissue and unilateral lymph node dissection.Compared surial, the cure rate, recurrence rate and complication rates.Results The survival of A, B, C three groups of patients was no statistical difference (P>0.05). Biochemical cure rate and postoperative recurrence rate was significant diferences (P< 0.05). A, B, C three groups of patients with laryngeal recurrent nerve injury and incidence of parathyroid function was significant diference (P< 0.05).Conclusion Compared with group A, group B and C has the same set of postoperative survival, but high cure rate, lower low parathyroid function and laryngeal recurrent nerve injury and lower incidence of cancer recurrence.